Does Pregabalin Improve Symptoms of Anxiety in Patients With Epilepsy? A Comparison With Sertraline
| Status: | Completed |
|---|---|
| Conditions: | Anxiety, Neurology, Epilepsy |
| Therapuetic Areas: | Neurology, Psychiatry / Psychology, Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 11/18/2012 |
| Start Date: | November 2009 |
| End Date: | December 2013 |
The aim of the study is to compare the safety & efficacy of sertraline (up to a dose of
200mg/day) & pregabalin (up to a dose of 300mg/day)for the treatment of symptoms of anxiety
in patients with epilepsy.
Inclusion Criteria:
- GAD-7 total score above 10.
- Have a diagnosis of a Partial Seizure Disorder.
- Have a Hamilton-A total score 20 and above.
- 18-80 years of age.
- Able to read at a fourth grade level.
- If a woman of childbearing age, agrees to use an acceptable means of birth control.
Exclusion Criteria:
- Unable to understand and sign a consent.
- Unable to follow instructions for the study.
- Displaying current suicidal ideation
- Having psychogenic non-epileptic seizures
- Have a history of drug or alcohol abuse.
- Use of any investigational drug within the last 30 days.
- Hypersensitivity reaction or other serious adverse event to PGB in prior trials.
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Rush University Medical Center Rush University Medical Center encompasses a 664-bed hospital serving adults and...
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