Varenicline-Aided Cigarette Reduction in Smokers Not Ready to Quit
| Status: | Completed |
|---|---|
| Conditions: | Smoking Cessation, Tobacco Consumers |
| Therapuetic Areas: | Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | 18 - 64 |
| Updated: | 4/21/2016 |
| Start Date: | January 2011 |
| End Date: | February 2014 |
The investigators will randomize smokers to receive 1) Varenicline + smoking
cessation/reduction counseling or 2) Placebo pill + smoking cessation/reduction counseling.
Neither the participants nor the research therapists/evaluators will know to which condition
(active or placebo pill) the participants have been assigned i.e., a double-blind study).
The medication and weekly counseling will occur for 28 days. Participants will complete
assessment measures just before the start of treatment (baseline), at the end-of-treatment,
at 1-month, 3-month, and at 6-months to determine if there are differences in tobacco use
between treatment groups.
cessation/reduction counseling or 2) Placebo pill + smoking cessation/reduction counseling.
Neither the participants nor the research therapists/evaluators will know to which condition
(active or placebo pill) the participants have been assigned i.e., a double-blind study).
The medication and weekly counseling will occur for 28 days. Participants will complete
assessment measures just before the start of treatment (baseline), at the end-of-treatment,
at 1-month, 3-month, and at 6-months to determine if there are differences in tobacco use
between treatment groups.
Inclusion Criteria:
- Must smoke at least 10 cigarettes per day for past 6-months
- Must have a working cellular or land-line phone
Exclusion Criteria:
- Must not be thinking of quitting in the next 30 days, but be interested in cutting
down- Must not regularly (more than 1x/month) use tobacco products other than
cigarettes
- Must not be currently receiving tobacco dependence treatment counseling
- Must not currently be taking varenicline, bupropion, nortriptyline, or any nicotine
preparations (gum, lozenge, patch, spray, inhaler)
- Must not have positive screen on SCID-I/NP Psychotic Screen
- Must have no contraindications to using varenicline, including pregnancy, as measured
by Medical History Form
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