Endolumenal Partial Myotomy for Esophageal Motility Disorders
| Status: | Recruiting |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 4/2/2016 |
| Start Date: | January 2011 |
| Contact: | Lee L Swanstrom, MD |
| Email: | lswanstrom@aol.com |
| Phone: | 503 281 0561 |
Endoscopic Submucosal Tunnel Dissection for Endolumenal Partial Myotomy of the Lower Esophageal Sphincter for Atypical Primary Motility Disorders Such as Achalasia and Esophageal Spasm
Achalasia and esophageal spasm are primary esophageal motility disorders where the lower
esophageal sphincter fails to relax in response to swallowing with no well understood
underlying cause. Surgical myotomy represents an appropriate therapeutic option. The purpose
of this study is to evaluate flexible endoscopic myotomy a novel therapeutic approach to
overcome the need for invasive surgery.
esophageal sphincter fails to relax in response to swallowing with no well understood
underlying cause. Surgical myotomy represents an appropriate therapeutic option. The purpose
of this study is to evaluate flexible endoscopic myotomy a novel therapeutic approach to
overcome the need for invasive surgery.
In this study, the investigators propose the use of a recent endolumenal technique for
partial myotomy in patients suffering from primary esophageal motility disorders.
Under general anesthesia patients will have upper endoscopy. Submucosal injection and
mucosal incision is created for entry into the submucosal space. A submucosal tunnel is then
created using a needle knife or blunt dissection as appropriate. Dissection will continue
distally beyond the lower esophageal sphincter. The inner circular muscle fibers will then
be divided to achieve an adequate myotomy length. The mucosal entry is then closed
appropriately.
Results will be compared to historical data of conventional Heller myotomies.
partial myotomy in patients suffering from primary esophageal motility disorders.
Under general anesthesia patients will have upper endoscopy. Submucosal injection and
mucosal incision is created for entry into the submucosal space. A submucosal tunnel is then
created using a needle knife or blunt dissection as appropriate. Dissection will continue
distally beyond the lower esophageal sphincter. The inner circular muscle fibers will then
be divided to achieve an adequate myotomy length. The mucosal entry is then closed
appropriately.
Results will be compared to historical data of conventional Heller myotomies.
Inclusion Criteria:
- Candidate for elective Heller myotomy
- Ability to undergo general anesthesia
- Ability to give informed consent
Exclusion Criteria:
- Previous mediastinal or esophageal surgery
- Contraindications for EGD
We found this trial at
1
site
4805 Northeast Glisan Street
Portland, Oregon 97213
Portland, Oregon 97213
(503) 215-1111
Providence Portland Medical Center We strive to give those we serve exceptional, compassionate health care...
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