Endolumenal Partial Myotomy for the Treatment of Esophageal Achalasia
| Status: | Recruiting |
|---|---|
| Conditions: | Gastrointestinal |
| Therapuetic Areas: | Gastroenterology |
| Healthy: | No |
| Age Range: | 18 - 85 |
| Updated: | 4/2/2016 |
| Start Date: | October 2010 |
| Contact: | Lee L Swanstrom, MD |
| Email: | lswanstrom@aol.com |
| Phone: | 503 281 0561 |
Endoscopic Submucosal Tunnel Dissection for Endolumenal Partial Myotomy of the Lower Esophageal Sphincter for Achalasia
Achalasia is a primary esophageal motility disorder where the lower esophageal sphincter
fails to relax in response to swallowing with no well understood underlying cause. Surgical
myotomy represents an appropriate therapeutic option. The purpose of this study is to
evaluate flexible endoscopic myotomy, a novel therapeutic approach to overcome the need for
invasive surgery.
fails to relax in response to swallowing with no well understood underlying cause. Surgical
myotomy represents an appropriate therapeutic option. The purpose of this study is to
evaluate flexible endoscopic myotomy, a novel therapeutic approach to overcome the need for
invasive surgery.
In this study, the investigators propose the use of a recent endolumenal technique for
partial myotomy in patients suffering from esophageal achalasia.
Under general anesthesia patients will have upper endoscopy. Submucosal injection and
mucosal incision is created for entry into the submucosal space. A submucosal tunnel is then
created using a needle knife or blunt dissection as appropriate. Dissection will continue
distally beyond the lower esophageal sphincter. The inner circular muscle fibers will then
be divided to achieve an adequate myotomy length. The mucosal entry is then closed
appropriately.
Results will be compared to historical data of conventional Heller myotomies.
partial myotomy in patients suffering from esophageal achalasia.
Under general anesthesia patients will have upper endoscopy. Submucosal injection and
mucosal incision is created for entry into the submucosal space. A submucosal tunnel is then
created using a needle knife or blunt dissection as appropriate. Dissection will continue
distally beyond the lower esophageal sphincter. The inner circular muscle fibers will then
be divided to achieve an adequate myotomy length. The mucosal entry is then closed
appropriately.
Results will be compared to historical data of conventional Heller myotomies.
Inclusion Criteria:
- Candidate for elective Heller myotomy
- Ability to undergo general anesthesia
- Ability to give informed consent
Exclusion Criteria:
- Previous mediastinal or esophageal surgery
- Contraindications for EGD
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