An Epidemiological Study of the Prevalence of Pre-Diabetes and Diabetes Among Air Force Personnel Who Fail the Air Force Physical Fitness Test at Nellis AFB, NV in 2011.

This will be a cross-sectional study. Subjects (Active duty Air Force personnel) will be
recruited from all male and female patients 18 years or older at the Michael O'Callaghan
Federal Hospital. A total of 1040 subjects will be recruited (520 subjects who have failed
their Air Force physical fitness test and 520 volunteers who have passed their physical
fitness test both within the last 6 months from recruitment into this study). Flyers,
posters, a presentation at the Health and Wellness Center (HAWC) during fitness and
nutritional counseling sessions and an advertisement in the Nellis Air Force Base paper will
be utilized to recruit potential subjects into this study. The research coordinator (a
civilian contractor) will give the presentation at the HAWC and will not be in uniform as to
avoid any undue influence. Subjects' participation in this study consists of 1 visit.

Screening:

- Review Medical History.

- Obtain Informed Consent and HIPAA Authorization

- You will be asked to provide researchers a copy of your AFPT results at Visit 1.

- You will be told to fast (not eat or drink anything) for at least 8 hours prior to
Visit 1.

Screening visit takes approximately 30 minutes.

Visit 1:

- Review past medical history.

- Patients will be asked to provide a copy of their AFPT results.

- Patients will be asked what exercises do they do and how often?

- What medications they were taking when they took their Air Force Fitness test.

- If they have a 1st degree relative (parents, children, siblings) with a diagnosis of
diabetes mellitus.

- Obtain height, weight, waist measurements, race, age and gender.

- Hemoglobin A1C and lipid panel blood levels drawn via 1 venipuncture (approximately
1-2 teaspoons for each blood test).

Visit 1 takes approximately 30 minutes.

Fasting lipid panel is being done to determine if those who fail their AFPT have higher
cardiovascular risks.

The data will then be compiled for statistical significance. This is a preliminary study to
evaluate whether or not this research study needs to be performed Air Force wide. The
patients Primary Care Manager (PCM) will be notified of any abnormal results and responsible
for notifying the patients of their test results via a Telephone Consult and will be
responsible for any subsequent treatment.

If at any time during the study, the subject decides to withdraw from the study, they will
be referred to their Primary Care Manager (PCM) to initiate standard of care treatment.

At the conclusion of the study, the data will be de-identified (i.e. all the patient
identifiers will be removed) and analyzed. A paper will be written and submitted to a
scientific journal.

Inclusion:

- Tricare Insurance Beneficiary (military insurance) receiving care at Nellis AFB

- Over the age of 18 and took their AFPT within the past 1 month.

Exclusion:

- Previous diagnosis of diabetes

- Pregnant or nursing