A Study to Compare the Concentrations of LY2189265 After Different Methods of Administration to Healthy Volunteers.

LY2189265 is an investigational drug being developed for the treatment of type 2 diabetes
mellitus. This study will compare the concentrations of LY2189265 using different methods of
administration. Subcutaneous (or SC- an injection just under the skin) intravenous (or IV -
into a vein in the arm) and intramuscular (IM - into the muscle of the left thigh). The
purpose of this study is to look at how much of the drug gets into the blood stream and how
long it takes the body to get rid of it when given by the methods above. The study is
divided into three parts, Part A, B and C. Volunteers will only be able to participate in
one part. All Participants in part A will receive a single IV dose of up to 0.1mg.
Participants in Part B will be given drug twice by IV and a a SC injection (1.5mg). Part B
of the study will occur after Part A because the dose of IV drug will depend on the results
of Part A. Part B of the study may not occur if the volunteers in Part A do not tolerate the
drug. Participants in Part C will also be given drug twice by a SC injection and an IM
injection, both doses will be 0.75 mg.