Cognitive Behavioral Therapy and the Nicotine Transdermal Patch for Cannabis Dependence and Nicotine Dependence
| Status: | Archived |
|---|---|
| Conditions: | Smoking Cessation, Psychiatric, Tobacco Consumers |
| Therapuetic Areas: | Psychiatry / Psychology, Pulmonary / Respiratory Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | August 2009 |
| End Date: | June 2011 |
The investigators are conducting a Stage 1 pilot feasibility study at McLean Hospital to
develop and refine a CBT intervention. The investigators aim to develop a feasible 10-week
integrated CBT intervention for the treatment of concurrent marijuana dependence and
nicotine dependence. The investigators hypothesize that the CBT intervention, in conjunction
with transdermal nicotine treatment, will reduce the use of marijuana and nicotine.
The investigators will conduct a Stage 1 pilot feasibility study at McLean Hospital to
develop and refine a CBT intervention. (FIGURE 1) Twelve subjects (50% female, ages 18-65)
who meet DSM-IV criteria for both marijuana and nicotine dependence and seek treatment to
stop using both marijuana and tobacco will receive individual CBT aimed at treating both
disorders, as well as transdermal nicotine treatment. Subjects will start with a 21-mg
nicotine patch for 6 weeks, followed by a taper to a 14-mg nicotine patch for 2 weeks and,
finally, a 7-mg nicotine patch for 2 weeks. Others will start with a 14-mg patch for 8
weeks followed by a 7-mg patch for 2 weeks. All participants will receive 10 weeks of
1-hour weekly CBT with an experienced clinician. Follow-up visits, scheduled at 4, 6, 8,
and 10 weeks, will evaluate of the durability of treatment effects on drug use and
psychosocial outcomes.
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