Safety and Tolerability Study of PCI-32765 Combined With Fludarabine/Cyclophosphamide/Rituximab (FCR) and Bendamustine/Rituximab (BR) in Chronic Lymphocytic Leukemia (CLL)
| Status: | Archived |
|---|---|
| Conditions: | Blood Cancer, Lymphoma |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | February 2011 |
| End Date: | March 2013 |
A Phase 1b, Multicenter, Open-label, Parallel-group Safety Study of a Bruton's Tyrosine Kinase (Btk) Inhibitor, PCI 32765, in Combination With Chemotherapy in Subjects With Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
The purpose of this study is to establish the safety of orally administered PCI-32765 in
combination with fludarabine/cyclophosphamide/rituximab (FCR) and bendamustine/rituximab
(BR) in patients with chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma(SLL).
This is a Phase 1b, open-label, parallel-group, nonrandomized, multicenter study of PCI
32765 420 mg once daily oral (PO) administration in combination with 2 different
chemotherapy regimens in subjects with relapsed/refractory chronic lymphocytic leukemia
(CLL)/small lymphocytic lymphoma (SLL).
We found this trial at
7
sites
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1515 Holcombe Blvd
Houston, Texas 77030
Houston, Texas 77030
713-792-2121
University of Texas M.D. Anderson Cancer Center The mission of The University of Texas MD...
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Sarah Cannon Cancer Center People who live with cancer
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601 Elmwood Ave
Rochester, New York 14642
Rochester, New York 14642
(585) 275-2100
Strong Memorial Hospital (University of Rochester School of Medicine) In addition to offering traditional and...
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