Phase 3 Trial in Squamous Non Small Cell Lung Cancer Subjects Comparing Ipilimumab Versus Placebo in Addition to Paclitaxel and Carboplatin
| Status: | Completed |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 9/21/2018 |
| Start Date: | January 16, 2011 |
| End Date: | August 22, 2017 |
Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab in Addition to Paclitaxel and Carboplatin Versus Placebo in Addition to Paclitaxel and Carboplatin in Subjects With Stage IV/Recurrent Non Small Cell Lung Cancer (NSCLC)
The purpose of the study is to determine whether Ipilimumab plus Paclitaxel and Carboplatin
will extend the lives of patients with squamous only non small cell lung cancer more than
placebo plus Paclitaxel and Carboplatin.
will extend the lives of patients with squamous only non small cell lung cancer more than
placebo plus Paclitaxel and Carboplatin.
The primary objective is to compare Overall Survival (OS) of participants with Stage
IV/recurrent NSCLC of squamous histology who have been randomized to ipilimumab in addition
to paclitaxel and carboplatin versus placebo in addition to paclitaxel and carboplatin, and
have received at least one dose of blinded study therapy (ipilimumab or placebo).
IV/recurrent NSCLC of squamous histology who have been randomized to ipilimumab in addition
to paclitaxel and carboplatin versus placebo in addition to paclitaxel and carboplatin, and
have received at least one dose of blinded study therapy (ipilimumab or placebo).
For more information regarding BMS clinical trial participation, please visit
www.BMSStudyConnect.com.
Inclusion Criteria:
- Non small cell lung cancer (NSCLC) - squamous cell
- Stage IV or recurrent NSCLC
- Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1
Exclusion Criteria:
- Brain Metastases
- Autoimmune diseases
We found this trial at
31
sites
Sharp Memorial Hospital Sharp Memorial Hospital offers clinical excellence with the latest technology and patient-centered...
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Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
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660 S Euclid Ave
Saint Louis, Missouri 63110
Saint Louis, Missouri 63110
(314) 362-5000
Washington University School of Medicine Washington University Physicians is the clinical practice of the School...
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VA Connecticut Healthcare System VA Connecticut encompasses an inpatient facility and Ambulatory Care Center in...
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