Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles
| Status: | Completed |
|---|---|
| Conditions: | Skin and Soft Tissue Infections, Cosmetic |
| Therapuetic Areas: | Dermatology / Plastic Surgery |
| Healthy: | No |
| Age Range: | 35 - Any |
| Updated: | 4/21/2016 |
| Start Date: | November 2010 |
| End Date: | December 2011 |
Double-blinded, Single-center, Parallel-arm Comparison Study of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage
The purpose of this study is to assess the comparative efficacy of retinol 1.0% and
tretinoin 0.02% in minimizing wrinkles, discoloration, roughness, and other signs of
moderate to severe photodamage. Our hypothesis is that both products will be of comparable
benefit.
tretinoin 0.02% in minimizing wrinkles, discoloration, roughness, and other signs of
moderate to severe photodamage. Our hypothesis is that both products will be of comparable
benefit.
Inclusion Criteria:
- Age 35 or over
- Moderate to severe photodamage
Exclusion Criteria:
- History of facial cosmetic surgery, facial resurfacing procedures, deep peels, or
facial fillers
- History of keloids or hypertrophic scars
- Use of oral steroids or oral retinoids (such as Accutane) in past 6 months
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