Oscillatory Versus Non-Oscillatory Nasal Continuous Airway Pressure Neonatal Respiratory Support

This study will seek to enroll neonates requiring Nasal Continuous Airway Pressure (NCPAP)
respiratory support and randomize them to either oscillatory (Osc-NCPAP, study group) or
non-oscillatory (NCPAP, control group) mode. The goal of the research is to determine if
Osc-NCPAP provides improved ventilation support compared to routine NCPAP, i.e. NCPAP
without oscillations. This will be measured by need for change to ventilator support,
improvement in pCO2 values, and reduction in respiratory rate and frequency of apnea during
the period of NCPAP treatment. Other respiratory outcomes will also be compared, including
time on NCPAP, time on High-Flow Nasal Cannula support following NCPAP, and time-averaged
PiO2 from start of study to end of respiratory treatment.