A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque Psoriasis



Status:Completed
Conditions:Psoriasis
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:18 - Any
Updated:10/14/2017
Start Date:March 2011
End Date:April 2013

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Phase 3 Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study Of The Efficacy And Safety Of 2 Oral Doses Of CP-690,550 In Subjects With Moderate To Severe Chronic Plaque Psoriasis

The main objective of this study is to compare the effects of CP-690,550 with the effects of
placebo in patients being treated for moderate to severe chronic plaque psoriasis. This
one-year study will also evaluate the safety and tolerability of CP-690,550 versus placebo.


Inclusion Criteria:

- Are 18 years or older with diagnosis for at least 12 months of moderate to severe
plaque psoriasis covering as least 10%of body surface area

- a Psoriasis Area and Severity Index (PASI) score of 12 and are considered to be
candidates for systemic or light therapy

- No evidence of active or latent tuberculosis

Exclusion Criteria:

- Non-plaque or drug induced forms of psoriasis

- cannot discontinue current oral, injectible or topical therapy for psoriasis or cannot
discontinue phototherapy (PUVA or UVB)

- any uncontrolled significant medical condition
We found this trial at
33
sites
New Haven, Connecticut 06511
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800 Washington St
Boston, Massachusetts 02111
(617) 636-5000
Tufts Medical Center Tufts Medical Center is an internationally-respected academic medical center – a teaching...
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104 SE 1st Avenue
Ocala, Florida 34471
352-629-5800
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Alpharetta, Georgia 30022
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Birmingham, Alabama 35209
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Boston, MA
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Dallas, Texas 75231
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Denver, Colorado 80209
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Houston, Texas 77030
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Indianapolis, Indiana 46256
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Indianapolis, IN
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Irvine, CA
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Johnston, Rhode Island 02919
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Knoxville, Tennessee 37917
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Lake Oswego, OR
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Madison, Wisconsin 53719
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550 1st Ave
New York, New York 10016
(212) 263-7300
New York University School of Medicine NYU School of Medicine has a proud history that...
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Newnan, Georgia 30263
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Norman, Oklahoma 73069
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Omaha, Nebraska 68144
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Raleigh, North Carolina 27612
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3100 Duraleigh Rd
Raleigh, North Carolina 27612
(919) 781-2514
Wake Research Associates, LLC Wake Research is an Organization of Unified Investigational Sites working closely...
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Rochester, New York 14623
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San Diego, California 92117
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Santa Monica, California 90404
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Spokane, Washington 99202
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Spokane, Washington 99202
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801 N Rutledge St
Springfield, Illinois 62702
(217) 545-8000
Southern Illinois University School of Medicine At SIU School of Medicine, research includes biologically oriented...
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Tampa, Florida 33615
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Winnipeg, Manitoba
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