A Study of Response-Guided Duration of Combination Therapy With GS-9451, Pegasys® and Copegus® With and Without Tegobuvir (GS-9190) in Previously Untreated Subjects With Genotype 1 Chronic Hepatitis C



Status:Archived
Conditions:Hepatitis
Therapuetic Areas:Immunology / Infectious Diseases
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:December 2010
End Date:December 2015

Use our guide to learn which trials are right for you!

Trial Summary
Trial Overview
Inclusion Criteria

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating 16 and 24 Weeks of Four-Drug Regimen and 24 Weeks of a Three-Drug Regimen of GS-9451, Peginterferon Alfa 2a (PEG, Pegasys®) and Ribavirin (RBV, Copegus®) With and Without Tegobuvir (GS-9190) Followed by Response Guided PEG and RBV in Treatment Naïve Subjects With Chronic Genotype 1 Hepatitis C Virus Infection (Protocol No. GS US 196 0140


This phase 2b study will evaluate the efficacy and safety of 16 and 24 weeks of a 4-drug
regimen with GS-9451 and Tegobuvir and 24 weeks of a 3-drug regimen of GS-9451 without
Tegobuvir, all with Peginterferon Alfa-2a (Pegasys®) and Ribavirin (Copegus®).



We found this trial at
83
sites
University of Chicago
5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
University of Chicago One of the world's premier academic and research institutions, the University of...
?
mi
from
Chicago, IL
Click here to add this to my saved trials
Avail Clinical Research
860 Peachwood Drive
DeLand, Florida 32720
(386) 740-0770
Site Overview Avail Clinical Research is a renowned and experienced clinical research site conducting Phase...
?
mi
from
DeLand, FL
Click here to add this to my saved trials
Johns Hopkins University
3400 N Charles St
Baltimore, Maryland 21205
410-516-8000
Johns Hopkins University The Johns Hopkins University opened in 1876, with the inauguration of its...
?
mi
from
Baltimore, MD
Click here to add this to my saved trials
Comprehensive Clinical Research
175 Cross Keys Rd.
Berlin, New Jersey 08009
856-753-7335
?
mi
from
Berlin, NJ
Click here to add this to my saved trials
Massachusetts General Hospital
185 Cambridge Street
Boston, Massachusetts 02114
617-724-5200
?
mi
from
Boston, MA
Click here to add this to my saved trials
Beth Israel Deaconess Medical Center
330 Brookline Ave
Boston, Massachusetts 02215
617-667-7000
Beth Israel Deaconess Medical Center Beth Israel Deaconess Medical Center (BIDMC) is one of the...
?
mi
from
Boston, MA
Click here to add this to my saved trials
Northwestern University
201 East Huron Street
Chicago, Illinois 60611
(847) 491-3741
Northwestern University Northwestern is recognized both nationally and internationally for the quality of its educational...
?
mi
from
Chicago, IL
Click here to add this to my saved trials
University of Cincinnati Medical Center
234 Goodman Dr
Cincinnati, Ohio 45229
(513) 584-1000
University of Cincinnati Medical Center Opening in 1823 as the country
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
UT Soutwestern Medical Center at Dallas
5303 Harry Hines Boulevard
Dallas, Texas 75390
(214) 648-3111
UT Soutwestern Medical Center at Dallas UT Southwestern Medical Center is distinctive for its overall...
?
mi
from
Dallas, TX
Click here to add this to my saved trials
University of Florida Gainesville
Gainesville, Florida 32611
(352) 392-3261
University of Florida Gainesville UF has a long history of established programs in international education,...
?
mi
from
Gainesville, FL
Click here to add this to my saved trials
Kelsey Research Foundation
5615 Kirby Dr.
Houston, Texas 77005
713-442-1223
?
mi
from
Houston, TX
Click here to add this to my saved trials
Indiana University
425 University Blvd.
Indianapolis, Indiana 46202
(317) 274-4591
Indiana University INDIANA UNIVERSITY is a major multi-campus public research institution, grounded in the liberal...
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Cedars-Sinai Medical Center
8700 Beverly Blvd # 8211
Los Angeles, California 90048
(1-800-233-2771)
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
?
mi
from
Los Angeles, CA
Click here to add this to my saved trials
North Shore University Hospital
300 Community Drive
Manhasset, New York 11030
(516) 562-0100
North Shore University Hospital North Shore-LIJ Health System includes 16 award-winning hospitals and nearly 400...
?
mi
from
Manhasset, NY
Click here to add this to my saved trials
Mount Sinai Hospital
1 Gustave L Levy Pl # 271
New York, New York 10029
 (212) 241-6500
Mount Sinai Med Ctr Founded in 1852, The Mount Sinai Hospital is a 1,171-bed, tertiary-care...
?
mi
from
New York, NY
Click here to add this to my saved trials
Washington Hospital Center
110 Irving St NW # 3B28
Washington, Washington DC 20010
?
mi
from
Washington, DC
Click here to add this to my saved trials
UNM Health Sciences Center
Albuquerque, New Mexico 87106
?
mi
from
Albuquerque, NM
Click here to add this to my saved trials
The North Texas Research Institute
Arlington, Texas 76012
?
mi
from
Arlington, TX
Click here to add this to my saved trials
Asheville Gastroenterology Associates, P.A.
Asheville, North Carolina 28801
?
mi
from
Asheville, NC
Click here to add this to my saved trials
Atlanta Gastroenterology Associates
Atlanta, Georgia 30342
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Liver Center of Atlanta
Atlanta, Georgia 30309
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Emory University Hospital - Atlanta
Atlanta, Georgia 30322
?
mi
from
Atlanta, GA
Click here to add this to my saved trials
Pacific Oaks Medical Group
Beverly Hills, California 90211
?
mi
from
Beverly Hills, CA
Click here to add this to my saved trials
Binghamton Gastroenterology
Binghamton, New York 13903
?
mi
from
Binghamton, NY
Click here to add this to my saved trials
University of Colorado, Boulder
Boulder, Colorado 80309
(303) 492-1411
University of Colorado, Boulder As the flagship university of the state of Colorado, CU-Boulder is...
?
mi
from
Boulder, CO
Click here to add this to my saved trials
Graves-Gilbert Clinic
Bowling Green, Kentucky 42101
?
mi
from
Bowling Green, KY
Click here to add this to my saved trials
Bach and Godofsky Infectious Diseases
Bradenton, Florida 34209
?
mi
from
Bradenton, FL
Click here to add this to my saved trials
Gastroenterology Associates
Bristol, Tennessee 37620
?
mi
from
Bristol, TN
Click here to add this to my saved trials
Albert Einstein College of Medicine
1300 Morris Park Ave
Bronx, New York 10461
(718) 430-2000
Albert Einstein College of Medicine The Albert Einstein College of Medicine of Yeshiva University is...
?
mi
from
Bronx, NY
Click here to add this to my saved trials
Medical University of South Carolina
171 Ashley Avenue
Charleston, South Carolina 29425
843-792-1414
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
?
mi
from
Charleston, SC
Click here to add this to my saved trials
eStudySite
Chula Vista, California 91911
?
mi
from
Chula Vista, CA
Click here to add this to my saved trials
Consultants for Clinical Research Inc.
Cincinnati, Ohio 45219
?
mi
from
Cincinnati, OH
Click here to add this to my saved trials
Case Western Reserve Univ
10900 Euclid Ave
Cleveland, Ohio 44106
216-368-2000
Case Western Reserve Univ Continually ranked among America's best colleges, Case Western Reserve University has...
?
mi
from
Cleveland, OH
Click here to add this to my saved trials
Dekalb Gastroenterology
Decatur, Georgia 30033
?
mi
from
Decatur, GA
Click here to add this to my saved trials
Infectious Disease Specialists of America
Decatur, Georgia 30033
?
mi
from
Decatur, GA
Click here to add this to my saved trials
Josephine Ford Cancer Center at Henry Ford Hospital
2799 W Grand Blvd
Detroit, Michigan 48202
(888) 777-4167
Josephine Ford Cancer Center at Henry Ford Hospital A diagnosis of cancer is one of...
?
mi
from
Detroit, MI
Click here to add this to my saved trials
Digestive Health Specialists of the Southeast
Dothan, Alabama 36305
?
mi
from
Dothan, AL
Click here to add this to my saved trials
Duke Univ Med Ctr
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
?
mi
from
Durham, NC
Click here to add this to my saved trials
South Denver Gastroenterology
Englewood, Colorado 80113
?
mi
from
Englewood, CO
Click here to add this to my saved trials
Metropolitan Research
Fairfax, Virginia 22031
?
mi
from
Fairfax, VA
Click here to add this to my saved trials
US Army Institute of Surgical Research
Ft Sam Houston, Texas 78234
?
mi
from
Ft Sam Houston, TX
Click here to add this to my saved trials
Memphis Gastroenterology Group
Germantown, Tennessee 38138
?
mi
from
Germantown, TN
Click here to add this to my saved trials
Palmetto Research
Hialeah, Florida 33016
?
mi
from
Hialeah, FL
Click here to add this to my saved trials
ID Care 105
Hillsborough, New Jersey 08844
?
mi
from
Hillsborough, NJ
Click here to add this to my saved trials
Digestive Associates of Houston
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Advanced Liver Therapies
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
Amcare Research Inc.
Houston, Texas 77090
?
mi
from
Houston, TX
Click here to add this to my saved trials
Research Specialists of Texas
Houston, Texas 77030
?
mi
from
Houston, TX
Click here to add this to my saved trials
IGRF
Indianapolis, Indiana 46237
?
mi
from
Indianapolis, IN
Click here to add this to my saved trials
Gastroenterology Associates, PA
Jackson, Mississippi 39202
?
mi
from
Jackson, MS
Click here to add this to my saved trials
Scripps HealthCare
LaJolla, California 92037
?
mi
from
LaJolla, CA
Click here to add this to my saved trials
University of Louisville Hospital
530 S Jackson St
Louisville, Kentucky 40202
502-562-3226
University of Louisville Hospital As the academic hospital at the heart of the Louisville Metro...
?
mi
from
Louisville, KY
Click here to add this to my saved trials
University of Wisconsin-Madison
Madison, Wisconsin 53706
(608) 263-2400
University of Wisconsin-Madison In achievement and prestige, the University of Wisconsin-Madison has long been recognized...
?
mi
from
Madison, WI
Click here to add this to my saved trials
University of Miami Hospital
1400 NW 12th Ave
Miami, Florida 33136
(305) 689-5511
University of Miami Hospital The University of Miami changed the face of modern health care...
?
mi
from
Miami, FL
Click here to add this to my saved trials
Alabama Liver & Digestive Specialists (Alds)
Montgomery, Alabama 36116
?
mi
from
Montgomery, AL
Click here to add this to my saved trials
Atlantic Research Affiliates, LLC
Morristown, New Jersey 07960
?
mi
from
Morristown, NJ
Click here to add this to my saved trials
James H. Quillen VA Medical Center
Mountain Home, Tennessee 37684
?
mi
from
Mountain Home, TN
Click here to add this to my saved trials
Columbia Medical Group -The First Clinic, Inc.
Nashville, Tennessee 37203
?
mi
from
Nashville, TN
Click here to add this to my saved trials
Synergy Clinical Research Center
National City, California 91950
?
mi
from
National City, CA
Click here to add this to my saved trials
UMDNJ-Robert Wood Johnson Medical Center
New Brunswick, New Jersey 08901
?
mi
from
New Brunswick, NJ
Click here to add this to my saved trials
Concorde Medical Group
New York, New York 10016
?
mi
from
New York, NY
Click here to add this to my saved trials
Cornell University, Weill Medical College
New York, New York 10021
?
mi
from
New York, NY
Click here to add this to my saved trials
New York University Langone Medical Center
550 1st Ave
New York, New York 10016
(212) 263-7300
New York University Langone Medical Center NYU NYU Langone Medical Center, a world-class, patient-centered, integrated,...
?
mi
from
New York, NY
Click here to add this to my saved trials
Columbia Presbyterian Med Ctr
722 W 168th St
New York, New York 10032
(212) 305-2500
Columbia Presbyterian Med Ctr On January 1, 1998, The New York Hospital publicly announced its...
?
mi
from
New York, NY
Click here to add this to my saved trials
Digestive and Liver Disease Specialists
Norfolk, Virginia 23502
?
mi
from
Norfolk, VA
Click here to add this to my saved trials
Scientific Clinical Research
North Miami, Florida 33161
?
mi
from
North Miami, FL
Click here to add this to my saved trials
Orlando Immunology Center
1701 North Mills Avenue
Orlando, Florida 32803
(407)647-3960
Orlando Immunology Center Orlando Immunology Center , or simply (OIC) is a part of Infectious...
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Florida Hospital
601 E Rollins St
Orlando, Florida 32803
(407) 303-5600
Florida Hospital Florida Hospital is one of the country
?
mi
from
Orlando, FL
Click here to add this to my saved trials
Mayo Clinic Phoenix
Phoenix, Arizona 85054
?
mi
from
Phoenix, AZ
Click here to add this to my saved trials
Minnesota Gastroenterology, P.A.
Plymouth, Minnesota 55446
?
mi
from
Plymouth, MN
Click here to add this to my saved trials
Liver Institute of Virginia, Bon Secours St. Mary's Hospital of Richmond
Richmond, Virginia 23229
?
mi
from
Richmond, VA
Click here to add this to my saved trials
Alamo Medical Research
San Antonio, Texas 78215
?
mi
from
San Antonio, TX
Click here to add this to my saved trials
RESEARCH and EDUCATION, INC
San Diego, California 92015
?
mi
from
San Diego, CA
Click here to add this to my saved trials
Medical Associates Research Group
San Diego, California 92123
?
mi
from
San Diego, CA
Click here to add this to my saved trials
VA Medical Center, San Francisco
San Francisco, California 94121
?
mi
from
San Francisco, CA
Click here to add this to my saved trials
California Pacific Medical Center
45 Castro Street
San Francisco, California 94114
(415) 600-6000
California Pacific Medical Center California Pacific Medical Center is one of the largest private, not-for-profit,...
?
mi
from
San Francisco, CA
Click here to add this to my saved trials
Virginia Mason Medical Center
Seattle, Washington 98101
(888) 862-2737
Virginia Mason Medical Center Established in 1920, Virginia Mason began as an 80-bed hospital with...
?
mi
from
Seattle, WA
Click here to add this to my saved trials
St Louis University
St Louis, Missouri 63104
?
mi
from
St Louis, MO
Click here to add this to my saved trials
University of Arizona
Tucson, Arizona 85721
(520) 621-2211
University of Arizona The University of Arizona is a premier, public research university. Established in...
?
mi
from
Tucson, AZ
Click here to add this to my saved trials
Options Health Research, LLC
Tulsa, Oklahoma 74104
?
mi
from
Tulsa, OK
Click here to add this to my saved trials
Kaiser Permanente
Vallejo, California 94589
?
mi
from
Vallejo, CA
Click here to add this to my saved trials
South Florida Center of Gastroenterology, LLC
Wellington, Florida 33414
?
mi
from
Wellington, FL
Click here to add this to my saved trials
Partners in Internal Medicine, P.C.
Worcester, Massachusetts 01608
?
mi
from
Worcester, MA
Click here to add this to my saved trials