Non-cancer Pain and Cognitive Impairment: A Disabling Relationship



Status:Completed
Conditions:Arthritis, Chronic Pain, Cognitive Studies
Therapuetic Areas:Musculoskeletal, Psychiatry / Psychology, Rheumatology
Healthy:No
Age Range:65 - Any
Updated:2/7/2015
Start Date:January 2011
End Date:August 2013
Contact:Joseph W Shega, MD
Email:jshega@medicine.bsd.uchicago.edu
Phone:773-834-7999

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Trial Summary
Trial Overview
Inclusion Criteria

Opioids Versus Extra Strength Acetaminophen for the Management of Moderate Persistent Non-cancer Pain

To compare the efficacy of long-acting oxycodone to extended-release acetaminophen in older
persons with no and mild to moderate cognitive impairment and persistent moderate or higher
intensity non-cancer lower extremity arthritis pain; and Describe the association of change
in non-cancer pain self-report with an older adults functional status (BPI and WOMAC and
brief physical performance measure) and to determine if cognitive status modifies this
relationship.


Inclusion Criteria:

1. age over 65

2. Pain at least 3 months duration

3. Pain greater in lower extremity than other anatomical site with ambulation

4. Pain self-report of moderate intensity of higher on an average day

5. Community-dwelling

6. Ambulatory

7. Physician states participants have decision-making capacity to enroll into the trial

8. Participants with cognitive impairment have a reliable caregiver

9. Inadequate pain relief from NSAIDS and/or acetaminophen in the past

Exclusion Criteria:

1. Current cancer requiring chemotherapy

2. History of addiction to opioids or other controlled substance

3. Consumes more than 2 alcoholic drinks a day

4. Severe balance disturbance

5. Intra-articular steroid injection in the past 6 weeks
We found this trial at
1
site
University of Chicago Medical Center Outpatient Senior Health Center South Shore
Chicago, Illinois 60649
?
mi
from
Chicago, IL
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