Collecting and Storing Samples of Bone Marrow and Blood From Patients With Relapsed Acute Lymphoblastic Leukemia or Non-Hodgkin Lymphoma



Status:Active, not recruiting
Conditions:Blood Cancer, Lymphoma, Leukemia
Therapuetic Areas:Oncology
Healthy:No
Age Range:Any - 30
Updated:7/21/2018
Start Date:September 25, 2006

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Trial Summary
Trial Overview
Inclusion Criteria

A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens

This research study is collecting and storing samples of bone marrow and blood from patients
with relapsed acute lymphoblastic leukemia or relapsed non-Hodgkin lymphoma. Collecting and
storing samples of bone marrow and blood from patients with cancer to study in the laboratory
may help doctors learn more about cancer and help predict the recurrence of cancer.

OBJECTIVES:

I. Establish a mechanism to bank specimens of tumor cells and host germline DNA from patients
with acute lymphoblastic leukemia (ALL) at first and subsequent relapse.

II. Make these specimens available to qualified researchers to study the biology of ALL.

OUTLINE: This is a multicenter study.

Patients undergo collection of bone marrow and peripheral blood at diagnosis of relapse
and/or at the end of the first month of treatment.

Patients are followed periodically for up to 10 years.

Inclusion Criteria:

- Diagnosis of acute lymphoblastic leukemia (ALL) or prior history of non-Hodgkin
lymphoma

- In first or subsequent marrow relapse with ? 25% blasts in bone marrow and/or
peripheral blood

- Bone marrow and/or peripheral blood samples (? 5 mL) required at the time of diagnosis
of relapse

- No concurrent systemic antileukemic treatment administered for current relapse

- Intrathecal chemotherapy allowed

- On-therapy relapse allowed
We found this trial at
169
sites
Children's Hospital Medical Center of Akron
Akron, Ohio 44308
Principal Investigator: Steven J. Kuerbitz
Phone: 330-543-3193
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University of New Mexico Cancer Center
1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
(505) 272-4946
Principal Investigator: Koh B. Boayue
Phone: 505-272-8699
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
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Lehigh Valley Hospital - Muhlenberg
2545 Schoenersville Rd
Bethlehem, Pennsylvania 18017
(484) 884-2200
Principal Investigator: Philip M. Monteleone
Phone: 484-884-2201
Lehigh Valley Hospital - Muhlenberg At Lehigh Valley Health Network, we continually go the extra...
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Children's Hospital of Alabama
1600 7th Avenue
Birmingham, Alabama 35233
(205) 638-9100
Principal Investigator: Alyssa T. Reddy
Phone: 205-975-1941
Children's Hospital of Alabama Children
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Roswell Park Cancer Institute
666 Elm Street
Buffalo, New York 14263
(716) 845-2300
Principal Investigator: Barbara J. Bambach
Phone: 716-845-8003
Roswell Park Cancer Institute Welcome to Roswell Park Cancer Institute (RPCI), America's first cancer center...
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University of Vermont College of Medicine
1 South Prospect Street
Burlington, Vermont 05401
802-656-8990
Principal Investigator: Alan C. Homans
Phone: 802-656-4101
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Burlington, VT
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Rainbow Babies and Children's Hospital
11100 Euclid Avenue
Cleveland, Ohio 44106
(216) 844-1000
Principal Investigator: Yousif (Joe) H. Matloub
Phone: 216-844-5437
Rainbow Babies and Children's Hospital UH Rainbow Babies & Children’s Hospital is a 244-bed, full-service...
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Nationwide Children's Hospital
700 Childrens Drive
Columbus, Ohio 43205
(616) 722-2000
Principal Investigator: Mark A. Ranalli
Phone: 614-722-2708
Nationwide Children's Hospital At Nationwide Children’s, we are creating the future of pediatric health care....
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Driscoll Children's Hospital
3533 South Alameda Street
Corpus Christi, Texas 78411
(361) 694-5000
Principal Investigator: M. C. Johnson
Phone: 361-694-5311
Driscoll Children's Hospital Driscoll Children's Hospital was built because Clara Driscoll's will requested that a...
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Medical City Dallas Hospital
7777 Forest Ln # C840
Dallas, Texas 75230
(972) 566-7000
Principal Investigator: Stanton C. Goldman
Phone: 972-566-6496
Medical City Dallas Hospital If you have concerns for your health, that of a family...
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Blank Children's Hospital
1200 Pleasant Street
Des Moines, Iowa 50309
(515) 241-KIDS
Principal Investigator: Wendy L. Woods-Swafford
Phone: 515-241-6729
Blank Children's Hospital Blank Children's Hospital is completely dedicated to meeting the unique health care...
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City of Hope Comprehensive Cancer Center
1500 E Duarte Rd
Duarte, California 91010
(626) 256-4673
Principal Investigator: Anna B. Pawlowska
Phone: 626-256-8723
City of Hope Comprehensive Cancer Center City of Hope is a leading research and treatment...
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Hurley Medical Center
1 Hurley Plaza
Flint, Michigan 48503
(810) 262-9000
Principal Investigator: Nkechi Onwuzurike
Phone: 810-262-9972
Hurley Medical Center From its founding in 1908, Hurley Medical Center has devoted itself to...
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Lee Memorial Health System
9981 S Healthpark Dr # 465
Fort Myers, Florida 33908
239-343-5000
Lee Memorial Health System Our origins can be traced to the Fall of 1916 when...
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Brooke Army Medical Center
3551 Roger Brooke Dr
Fort Sam Houston, Texas 78234
(210) 916-4141
Phone: 210-916-4837
Brooke Army Medical Center Brooke Army Medical Center (BAMC) is the Flagship of Army Medicine!...
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Helen DeVos Children's Hospital at Spectrum Health
100 Michigan Street Northeast
Grand Rapids, Michigan 49503
616.391.9000
Principal Investigator: David S. Dickens
Phone: 616-267-1925
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Connecticut Children's Medical Center
282 Washington St
Hartford, Connecticut 06106
(860) 545-9000
Principal Investigator: Michael S. Isakoff
Phone: 860-545-9981
Connecticut Children's Medical Center Connecticut Children’s Medical Center is a nationally recognized, 187-bed not-for-profit children’s...
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University of Mississippi Medical Center
2500 N State St
Jackson, Mississippi 39216
(601) 984-1000
Principal Investigator: Gail C. Megason
Phone: 601-815-6700
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Bronson Methodist Hospital
524 South Park Street
Kalamazoo, Michigan 49007
(269) 341-7654
Principal Investigator: Katharina E. Elliott
Phone: 269-341-8580
Bronson Methodist Hospital Our healthcare system serves patients and families throughout southwest Michigan and northern...
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Children's Mercy Hospital
2401 Gillham Rd
Kansas City, Missouri 64108
(816) 234-3000
Principal Investigator: Maxine L. Hetherington
Phone: 816-234-3265
Children's Mercy Hospital Children's Mercy Hospitals and Clinics continues redefining pediatric medicine throughout the Midwest...
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University Medical Center of Southern Nevada
1800 West Charleston Boulevard
Las Vegas, Nevada 89102
(702) 383-2000
University Medical Center of Southern Nevada University Medical Center is dedicated to providing the highest...
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University of Arkansas for Medical Sciences
529 West Markham Street
Little Rock, Arkansas 72205
(501) 686-7000
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Childrens Hospital Los Angeles
4650 Sunset Blvd
Los Angeles, California 90027
 (323) 660-2450
Principal Investigator: Leo Mascarenhas
Phone: 323-361-4110
Childrens Hospital Los Angeles Children's Hospital Los Angeles is a 501(c)(3) nonprofit hospital for pediatric...
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Covenant Children's Hospital
4015 22nd Place
Lubbock, Texas 79410
806-725-0000
Principal Investigator: Latha Prasannan
Phone: 806-725-8000
Covenant Children's Hospital Every child is different. And when they're sick or injured, they deserve...
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Children's Hospital Central California
9300 Valley Children's Pl
Madera, California 93720
(559) 353-3000
Principal Investigator: Vonda L. Crouse
Phone: 866-353-5437
Children's Hospital Central California The Children's Hospital Central California is a not-for-profit, state-of-the-art children’s hospital...
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Children's Hospital of The King's Daughters
601 Children's Lane
Norfolk, Virginia 23507
(757) 668-7000
Principal Investigator: Eric J. Lowe
Phone: 757-668-7243
Children's Hospital of The King's Daughters Children
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Children's Hospital and Research Center Oakland
747 52nd St
Oakland, California 94609
(510) 428-3000
Principal Investigator: Carla B. Golden
Phone: 510-450-7600
Children's Hospital and Research Center Oakland For nearly 100 years, Children's Hospital & Research Center...
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Children's Hospital of Orange County
1201 W La Veta Ave
Orange, California 92868
(714) 997-3000
Principal Investigator: Violet Shen
Phone: 714-997-3000
Children's Hospital of Orange County For more than 45 years, CHOC Children’s has been steadfastly...
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Nemours Children's Clinic - Orlando
1717 South Orange Avenue # 100
Orlando, Florida 32806
(407) 650-7000
Phone: 407-650-7230
Nemours Children's Clinic - Orlando Located near downtown Orlando, Nemours Children’s Clinic, Orlando is a...
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Nemours Children's Clinic - Pensacola
5153 North 9th Avenue
Pensacola, Florida 32504
(850) 505-4700
Principal Investigator: Jeffrey H. Schwartz
Phone: 904-697-3529
Nemours Children's Clinic - Pensacola Nemours Children’s Clinic, Pensacola serves children and families in northwest...
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Saint Jude Midwest Affiliate
530 Northeast Glen Oak Avenue
Peoria, Illinois 61603
(309) 624-4945
Principal Investigator: Karen S. Fernandez
Phone: 309-624-9848
Saint Jude Midwest Affiliate The Jim and Trudy Maloof St. Jude Midwest Affiliate Clinic was...
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Children's Hospital of Philadelphia
South 34th Street
Philadelphia, Pennsylvania 19104
 215-590-1000
Principal Investigator: Susan R. Rheingold
Phone: 215-590-2810
Children's Hospital of Philadelphia Since its start in 1855 as the nation's first hospital devoted...
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Children's Hospital of Pittsburgh of UPMC
4401 Penn Avenue
Pittsburgh, Pennsylvania 15224
412-692-5325
Principal Investigator: Arthur K. Ritchey
Phone: 412-692-5573
Children's Hospital of Pittsburgh of UPMC UPMC is one of the leading nonprofit health systems...
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Oregon Health and Science University
3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
503 494-8311
Principal Investigator: Linda C. Stork
Phone: 503-494-1080
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Rhode Island Hospital
593 Eddy Street
Providence, Rhode Island 02903
401-444-4000
Principal Investigator: Jennifer J. Greene Welch
Phone: 401-444-1488
Rhode Island Hospital Founded in 1863, Rhode Island Hospital in Providence, RI, is a private,...
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University of Rochester
60 Crittenden Blvd # 70
Rochester, New York 14642
(585) 275-2121
Principal Investigator: Jeffrey R. Andolina
Phone: 585-275-5830
University of Rochester The University of Rochester is one of the country's top-tier research universities....
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Methodist Children's Hospital of South Texas
7700 Floyd Curl Dr
San Antonio, Texas 78229
(210) 575-7000
Principal Investigator: Gerardo Quezada
Phone: 210-575-6254
Methodist Children's Hospital of South Texas Methodist Children
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University of Texas Health Science Center at San Antonio
4502 Medical Drive
San Antonio, Texas 78284
(210) 567-7000
Principal Investigator: Anne-Marie R. Langevin
Phone: 210-450-3800
University of Texas Health Science Center at San Antonio The University of Texas Health Science...
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Naval Medical Center - San Diego
34800 Bob Wilson Dr,
San Diego, California 92134
(619) 532-6400
Naval Medical Center - San Diego We are the largest and most comprehensive military healthcare...
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Rady Children's Hospital - San Diego
3020 Childrens way
San Diego, California 92123
(858) 576-1700
Principal Investigator: William D. Roberts
Phone: 858-966-8035
Rady Children's Hospital - San Diego Rady Children's Hospital-San Diego is the region’s pediatric medical...
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Tampa General Hospital
1 Tampa General Cir
Tampa, Florida 33606
(813) 844-7000
Principal Investigator: Cameron K. Tebbi
Phone: 800-882-4123
Tampa General Hospital In a diverse city known for its rich culture and beautiful beaches,...
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New York Medical College
40 Sunshine Cottage Road
Valhalla, New York 10595
(914) 594-4000
Principal Investigator: Jessica C. Hochberg
Phone: 914-594-3794
New York Medical College The College was founded in 1860 by a group of New...
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Alfred I. duPont Hospital for Children
1600 Rockland Road
Wilmington, Delaware 19803
(302) 651-4200
Principal Investigator: Jeffrey H. Schwartz
Phone: 904-697-3529
Alfred I. duPont Hospital for Children Nemours began more than 70 years ago with the...
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Albany Medical Center
Albany, New York 12208
Principal Investigator: Vikramjit S. Kanwar
Phone: 518-262-3368
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Texas Tech University Health Sciences Center at Amarillo
Amarillo, Texas 79106
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Mission Hospital-Memorial Campus
Asheville, North Carolina 28801
Principal Investigator: Douglas J. Scothorn
Phone: 828-213-4150
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Children's Healthcare of Atlanta - Egleston
Atlanta, Georgia 30322
Principal Investigator: Glen Lew
Phone: 404-785-3510
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Children's Hospital Colorado
13123 E 16th Ave
Aurora, Colorado 80045
(720) 777-1234
Principal Investigator: Kelly W. Maloney
Phone: 720-777-6672
Children's Hospital Colorado At Children's Hospital Colorado, we see more, treat more and heal more...
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Sinai Hospital of Baltimore
2401 W Belvedere Ave
Baltimore, Maryland 21215
(410) 601-9000
Principal Investigator: Joseph M. Wiley
Phone: 410-601-6120
Sinai Hospital of Baltimore Sinai Hospital of Baltimore provides a broad array of high-quality, cost-effective...
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University of Maryland Greenebaum Cancer Center
22 South Greene Street
Baltimore, Maryland 21201
410-328-7904
Principal Investigator: Teresa A. York
Phone: 800-888-8823
University of Maryland Greenebaum Cancer Center The University of Maryland Marlene and Stewart Greenebaum Cancer...
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Johns Hopkins University-Sidney Kimmel Cancer Center
401 North Broadway
Baltimore, Maryland 21287
410-955-5000
Principal Investigator: Patrick A. Brown
Phone: 410-955-8804
Johns Hopkins University-Sidney Kimmel Cancer Center The name Johns Hopkins has become synonymous with excellence...
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Walter Reed National Military Medical Center
8901 Rockville Pike
Bethesda, Maryland 20889
(301) 295-4000
Principal Investigator: Anne B. Warwick
Phone: 301-319-2100
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University of Alabama at Birmingham Cancer Center
Birmingham, Alabama 35233
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Saint Luke's Mountain States Tumor Institute
100 E Idaho St
Boise, Idaho 83712
(208) 381-2711
Principal Investigator: Eugenia Chang
Phone: 208-381-2974
Saint Luke's Mountain States Tumor Institute For more than 100 years, St. Luke
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Montefiore Medical Center - Moses Campus
Bronx, New York 10467
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UNC Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina 27599
Principal Investigator: Stuart H. Gold
Phone: 877-668-0683
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West Virginia University Charleston Division
3110 MacCorkle Avenue Southeast
Charleston, West Virginia 25304
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Carolinas Medical Center / Levine Cancer Institute
Charlotte, North Carolina 28204
Principal Investigator: Joel A. Kaplan
Phone: 704-355-2884
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Novant Health Presbyterian Medical Center
Charlotte, North Carolina 28204
Principal Investigator: Paulette C. Bryant
Phone: 704-384-5369
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T C Thompson Children's Hospital
Chattanooga, Tennessee 37403
Principal Investigator: Manoo G. Bhakta
Phone: 423-778-7289
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Lurie Children's Hospital- Chicago
Chicago, Illinois 60614
Principal Investigator: Elaine R. Morgan
Phone: 773-880-4562
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Univ of Illinois
1200 West Harrison Stree
Chicago, Illinois 60607
(312) 996-4350
Principal Investigator: Mary L. Schmidt
Phone: 312-355-3046
Univ of Illinois A major research university in the heart of one of the world's...
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University of Chicago Comprehensive Cancer Center
5841 S Maryland Ave
Chicago, Illinois 60637
1-773-702-6180
Principal Investigator: Susan L. Cohn
Phone: 773-834-1329
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Cleveland Clinic Foundation
2049 E 100th St
Cleveland, Ohio 44106
(216) 444-2200
Principal Investigator: Aron Flagg
Phone: 866-223-8100
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Columbia Regional
Columbia, Missouri 65201
Principal Investigator: Thomas W. Loew
Phone: 573-884-4277
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Palmetto Health Richland
5 Richland Medical Park Dr
Columbia, South Carolina 29203
(803) 434-7000
Principal Investigator: Ronnie W. Neuberg
Phone: 803-434-3680
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UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas 75390
Principal Investigator: Tamra L. Slone
Phone: 214-648-7097
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Dayton Children's Hospital
Dayton, Ohio 45404
Principal Investigator: Ayman A. El-Sheikh
Phone: 937-641-3296
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Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center
Denver, Colorado 80218
Principal Investigator: Jennifer J. Clark
Phone: 866-775-6246
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Wayne State University/Karmanos Cancer Institute
4160 John R St #2122
Detroit, Michigan 48201
(313) 833-1785
Principal Investigator: Madhvi Rajpurkar
Phone: 313-576-9363
Wayne State University/Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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Saint John Hospital and Medical Center
22101 Moross Rd
Detroit, Michigan 48236
(313) 343-4000
Principal Investigator: Hadi Sawaf
Phone: 313-343-3166
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Kaiser Permanente Downey Medical Center
9333 Imperial Highway
Downey, California 90242
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Duke Univ Med Ctr
2301 Erwin Rd
Durham, North Carolina 27710
919-684-8111
Principal Investigator: Susan G. Kreissman
Phone: 888-275-3853
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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Michigan State University Clinical Center
East Lansing, Michigan 48824
Principal Investigator: Renuka Gera
Phone: 517-975-9547
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Sanford Broadway Medical Center
801 Broadway North
Fargo, North Dakota 58122
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Broward Health Medical Center
1600 S Andrews Ave
Fort Lauderdale, Florida 33316
(954) 355-4400
Principal Investigator: Hector M. Rodriguez-Cortes
Phone: 954-355-5346
Broward Health Medical Center Broward Health, providing service for more than 75 years, is a...
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Golisano Children's Hospital of Southwest Florida
Fort Myers, Florida 33908
Principal Investigator: Emad K. Salman
Phone: 239-343-5333
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Cook Children's Medical Center
801 7th Avenue
Fort Worth, Texas 76104
(682) 885-4000
Principal Investigator: Kenneth M. Heym
Phone: 682-885-1712
Cook Children's Medical Center Cook Children's Health Care System is a not-for-profit, nationally recognized pediatric...
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University of Florida Health Science Center ?? Gainesville
1600 Southwest Archer Road
Gainesville, Florida 32610
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Saint Vincent Hospital Cancer Center Green Bay
835 S Van Buren St
Green Bay, Wisconsin 54301
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East Carolina University
1001 E 5th St
Greenville, North Carolina 27858
(252) 328-6131
Principal Investigator: George E. Hucks
Phone: 252-744-8199
East Carolina University Whether it's meeting the demand for more teachers and healthcare professionals or...
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BI-LO Charities Children's Cancer Center
900 West Faris Rd.
Greenville, South Carolina 29605
(864)455-8898
Principal Investigator: Nichole L. Bryant
Phone: 864-455-5164
BI-LO Charities Children's Cancer Center The BI-LO Charities Children
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Greenville Cancer Treatment Center
Greenville, South Carolina 29605
Principal Investigator: Nichole L. Bryant
Phone: 864-241-6251
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Hackensack University Medical Center
30 Prospect Ave
Hackensack, New Jersey 07601
(201) 996-2000
Principal Investigator: Burton E. Appel
Phone: 201-996-2879
Hackensack University Medical Center Hackensack University Medical Center, part of the Hackensack University Health Network,...
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Penn State Children's Hospital
Hershey, Pennsylvania 17033
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Memorial Regional Hospital/Joe DiMaggio Children's Hospital
Hollywood, Florida 33021
Principal Investigator: Iftikhar Hanif
Phone: 954-265-2234
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University of Hawaii Cancer Center
Honolulu, Hawaii 96813
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Kapiolani Medical Center for Women and Children
1319 Punahou St
Honolulu, Hawaii 96826
(808) 983-6000
Principal Investigator: Robert W. Wilkinson
Phone: 808-983-6090
Kapiolani Medical Center for Women and Children Hawai‘i Pacific Health is an integrated health care...
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Honolulu, HI
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Riley Hospital for Children
705 Riley Hospital Dr
Indianapolis, Indiana 46202
(317) 944-5000
Principal Investigator: Robert J. Fallon
Phone: 317-948-0616
Riley Hospital for Children Riley Hospital for Children at IU Health is a place of...
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Indianapolis, IN
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Saint Vincent Hospital and Health Care Center
Indianapolis, Indiana 46260
Principal Investigator: Bassem I. Razzouk
Phone: 317-338-2194
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Indianapolis, IN
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University of Iowa - Holden Comprehensive Cancer Center
Iowa City, Iowa 52242
Principal Investigator: Ayman A. El-Sheikh
Phone: 800-237-1225
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Iowa City, IA
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Nemours Children's Clinic - Jacksonville
Jacksonville, Florida 32207
Principal Investigator: Jeffrey H. Schwartz
Phone: 904-697-3529
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Jacksonville, FL
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Kalamazoo Center for Medical Studies
Kalamazoo, Michigan 49008
Principal Investigator: Jeffrey S. Lobel
Phone: 800-227-2345
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Kalamazoo, MI
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University of Kansas Cancer Center
Kansas City, Kansas 66160
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Kansas City, KS
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East Tennessee Children's Hospital
2018 W Clinch Ave
Knoxville, Tennessee 37916
(865) 541-8000
Principal Investigator: Ray C. Pais
Phone: 865-541-8266
East Tennessee Children's Hospital East Tennessee Children's Hospital is a not-for-profit, private, independent pediatric medical...
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Knoxville, TN
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Sunrise Hospital and Medical Center
Las Vegas, Nevada 89109
Principal Investigator: Nik Farahana N. Rashid
Phone: 702-384-0013
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Las Vegas, NV
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Summerlin Hospital Medical Center
Las Vegas, Nevada 89144
Principal Investigator: Jonathan Bernstein
Phone: 702-384-0013
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Las Vegas, NV
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Children's Specialty Center of Nevada II
Las Vegas, Nevada 89109
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Las Vegas, NV
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Nevada Cancer Research Foundation CCOP
601 South Rancho Drive Suite C-26
Las Vegas, Nevada 89106
(702) 384-0013
Principal Investigator: Jonathan Bernstein
Phone: 702-384-0013
Nevada Cancer Research Foundation CCOP The Nevada Cancer Research Foundation Community Clinical Oncology Program (NCRF-CCOP)...
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Las Vegas, NV
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Dartmouth Hitchcock Medical Center
1 Medical Center Dr
Lebanon, New Hampshire 03756
 (603) 650-5000
Principal Investigator: Sara Chaffee
Phone: 800-639-6918
Dartmouth Hitchcock Medical Center Dartmouth-Hitchcock is a national leader in patient-centered health care and building...
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Lebanon, NH
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University of Kentucky, Markey Cancer Center
Lexington, Kentucky
Principal Investigator: Lars M. Wagner
Phone: 859-257-3379
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Lexington, KY
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