Study of Kidney Tumors in Younger Patients
Status: | Recruiting |
---|---|
Conditions: | Colorectal Cancer, Cancer, Cancer, Hematology, Kidney Cancer |
Therapuetic Areas: | Hematology, Oncology |
Healthy: | No |
Age Range: | Any - 29 |
Updated: | 2/24/2019 |
Start Date: | February 27, 2006 |
Renal Tumors Classification, Biology, and Banking Study
This research trial studies kidney tumors in younger patients. Collecting and storing samples
of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may
help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify
biomarkers related to cancer.
of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may
help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify
biomarkers related to cancer.
PRIMARY OBJECTIVES:
I. Classify patients with renal tumors by histological categorization, surgico-pathological
stage, presence of metastases, age at diagnosis, tumor weight, and loss of heterozygosity for
chromosomes 1p and 16q, to define eligibility for a series of therapeutic studies. (Loss of
heterozygosity [LOH] testing discontinued as of April 2014) II. Maintain a biological samples
bank to make specimens available to scientists to evaluate additional potential biological
prognostic variables and for the conduct of other research by scientists.
SECONDARY OBJECTIVES:
I. Monitor outcome for those patients who are not eligible for a subsequent therapeutic
study.
II. Describe whether the pulmonary tumor burden correlates with outcome in stage IV patients.
III. Describe the sensitivity and specificity of abdominal computed tomography (CT) by
comparison with surgical and pathologic findings for identification of local tumor spread
beyond the renal capsule to adjacent muscle and organs, lymph node involvement at the renal
hilum and in the retroperitoneum, preoperative tumor rupture, and metastases to the liver.
IV. Compare the sensitivity and specificity of pre-operative abdominal CT scan and magnetic
resonance imaging (MRI) for the identification and differentiation of nephrogenic rests and
Wilms' tumor in children with multiple renal lesions.
V. Correlate the method of conception (natural vs assisted reproductive technology) with the
development of Wilms' tumor.
VI. To evaluate the frequency of integrase interactor 1 (INI1) mutations in renal and
extrarenal malignant rhabdoid tumor of the kidney and to determine the incidence of germline
and inherited versus somatic mutations to facilitate clinical correlations on the companion
study AREN0321. (INI1 testing discontinued as of April 2014)
OUTLINE:
Tumor tissue, blood, and urine samples are collected for research studies, including
immunohistochemistry. CT scans and MRIs are also performed. Loss of heterozygosity analyses
(chromosome 1p and 16q) are performed by extraction of DNA. DNA polymorphisms are assayed by
polymerase chain reaction using standard methodology. Leftover specimens are archived for
future studies. (LOH and INI1 testing discontinued as of April 2014)
Patients are followed up periodically for 5 years.
I. Classify patients with renal tumors by histological categorization, surgico-pathological
stage, presence of metastases, age at diagnosis, tumor weight, and loss of heterozygosity for
chromosomes 1p and 16q, to define eligibility for a series of therapeutic studies. (Loss of
heterozygosity [LOH] testing discontinued as of April 2014) II. Maintain a biological samples
bank to make specimens available to scientists to evaluate additional potential biological
prognostic variables and for the conduct of other research by scientists.
SECONDARY OBJECTIVES:
I. Monitor outcome for those patients who are not eligible for a subsequent therapeutic
study.
II. Describe whether the pulmonary tumor burden correlates with outcome in stage IV patients.
III. Describe the sensitivity and specificity of abdominal computed tomography (CT) by
comparison with surgical and pathologic findings for identification of local tumor spread
beyond the renal capsule to adjacent muscle and organs, lymph node involvement at the renal
hilum and in the retroperitoneum, preoperative tumor rupture, and metastases to the liver.
IV. Compare the sensitivity and specificity of pre-operative abdominal CT scan and magnetic
resonance imaging (MRI) for the identification and differentiation of nephrogenic rests and
Wilms' tumor in children with multiple renal lesions.
V. Correlate the method of conception (natural vs assisted reproductive technology) with the
development of Wilms' tumor.
VI. To evaluate the frequency of integrase interactor 1 (INI1) mutations in renal and
extrarenal malignant rhabdoid tumor of the kidney and to determine the incidence of germline
and inherited versus somatic mutations to facilitate clinical correlations on the companion
study AREN0321. (INI1 testing discontinued as of April 2014)
OUTLINE:
Tumor tissue, blood, and urine samples are collected for research studies, including
immunohistochemistry. CT scans and MRIs are also performed. Loss of heterozygosity analyses
(chromosome 1p and 16q) are performed by extraction of DNA. DNA polymorphisms are assayed by
polymerase chain reaction using standard methodology. Leftover specimens are archived for
future studies. (LOH and INI1 testing discontinued as of April 2014)
Patients are followed up periodically for 5 years.
Inclusion Criteria:
- Patients with the first occurrence of any tumor of the kidney identified on CT scan or
MRI are eligible for this study; histologic diagnosis is not required prior to
enrollment but is required for all patients once on study
- Eligible tumors include (but are not limited to):
- Nephroblastic tumors
- Nephroblastoma (Wilms' tumor) (favorable histology, anaplasia [diffuse,
focal])
- Nephrogenic rests and nephroblastomatosis
- Cystic nephroma and cystic partially differentiated nephroblastoma
- Metanephric tumors (metanephric adenoma, metanephric adenofibroma,
metanephric stromal tumor)
- Mesoblastic nephroma (cellular, classic, mixed)
- Clear cell sarcoma
- Rhabdoid tumor (any malignant rhabdoid tumor occurring outside the central
nervous system [CNS])
- Renal epithelioid tumors of childhood (papillary renal cell carcinoma, medullary
renal cell carcinoma, renal tumors associated with Xp11.2 translocations,
oncocytic renal neoplasms after neuroblastoma)
- Angiolipoma
- Ossifying renal tumor of infancy
- Patients with the first occurrence of the following tumors are also eligible:
- Extrarenal nephroblastoma or extrarenal neprogenic rests
- Malignant rhabdoid tumor occurring anywhere outside the Central Nervous System
- Required specimens, reports, and copies of imaging studies must be available for
submission or must become available during the required timeframe
- For ALL patients (with exception of bilateral, bilaterally predisposed or unilateral
tumor in solitary kidney planning to enroll without biopsy), the following submissions
are required:
- A complete set of recut hematoxylin and eosin (H & E) slides**
- Representative formalin-fixed paraffin-embedded tissue block or if a block is
unavailable, 10 unstained slides from a representative block of tumor**
- Institutional pathology report, transmittal form and pathology checklist
- Copies of images and institutional reports of CT and/or MRI abdomen and pelvis
- Copies of images and institutional report of CT chest for all malignant tumors
- Institutional surgical report(s)
- Tissue must be from diagnosis, prior to any chemotherapy or radiation
- For patients with clinical features and required imaging findings consistent with the
eligibility for the bilateral study, AREN0534 (or successor study), confirmed by
central review, biopsy is not required; however, if biopsy is done, tissue must be
submitted as for other renal tumors, and initial risk assignment will require
pathology and surgical rapid central reviews; transmittal form and pathology checklist
are also needed
- Patients with extrarenal Wilms tumor must have tumor tissue available for central
review
- Patients with extra-CNS malignant rhabdoid tumor must have tumor tissue available for
central review
- All patients and/or their parents or legal guardians must sign a written informed
consent
- All institutional, Food and Drug Administration (FDA), and National Cancer Institute
(NCI) requirements for human studies must be met
We found this trial at
213
sites
7777 Forest Ln # C840
Dallas, Texas 75230
Dallas, Texas 75230
(972) 566-7000
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Principal Investigator: Stanton C. Goldman
Phone: 972-566-5588
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1201 Camino de Salud Northeast
Albuquerque, New Mexico 87131
Albuquerque, New Mexico 87131
(505) 272-4946
![University of New Mexico Cancer Center](/wp-content/uploads/logos/university-of-new-mexico-cancer-center.jpg)
Principal Investigator: John F. Kuttesch
Phone: 505-925-0366
University of New Mexico Cancer Center It’s been 40 years since the New Mexico State...
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4900 Mueller Boulevard
Austin, Texas 78723
Austin, Texas 78723
(512) 324-0000
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Principal Investigator: Amy C. Fowler
Phone: 512-324-8022
Dell Children's Medical Center of Central Texas Welcome to Dell Children
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2545 Schoenersville Rd
Bethlehem, Pennsylvania 18017
Bethlehem, Pennsylvania 18017
(484) 884-2200
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Principal Investigator: Philip M. Monteleone
Phone: 484-884-2201
Lehigh Valley Hospital - Muhlenberg At Lehigh Valley Health Network, we continually go the extra...
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1600 7th Avenue
Birmingham, Alabama 35233
Birmingham, Alabama 35233
(205) 638-9100
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Principal Investigator: Matthew A. Kutny
Phone: 205-934-0309
Children's Hospital of Alabama Children
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666 Elm Street
Buffalo, New York 14263
Buffalo, New York 14263
(716) 845-2300
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Principal Investigator: Matthew J. Barth
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1 South Prospect Street
Burlington, Vermont 05401
Burlington, Vermont 05401
802-656-8990
Principal Investigator: Jessica L. Heath
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1300 Jefferson Park Avenue
Charlottesville, Virginia 22908
Charlottesville, Virginia 22908
434-243-6784
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Principal Investigator: William C. Petersen
Phone: 434-243-6303
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3333 Burnet Avenue # Mlc3008
Cincinnati, Ohio 45229
Cincinnati, Ohio 45229
1-513-636-4200
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Principal Investigator: James I. Geller
Phone: 513-636-2799
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11100 Euclid Avenue
Cleveland, Ohio 44106
Cleveland, Ohio 44106
(216) 844-1000
![Rainbow Babies and Children's Hospital](/wp-content/uploads/logos/rainbow-babies-and-children-s-hospital.jpg)
Principal Investigator: John J. Letterio
Phone: 216-844-5437
Rainbow Babies and Children's Hospital UH Rainbow Babies & Children’s Hospital is a 244-bed, full-service...
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700 Childrens Drive
Columbus, Ohio 43205
Columbus, Ohio 43205
(616) 722-2000
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Principal Investigator: Mark A. Ranalli
Phone: 614-722-2708
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3533 South Alameda Street
Corpus Christi, Texas 78411
Corpus Christi, Texas 78411
(361) 694-5000
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Principal Investigator: Nkechi I. Mba
Phone: 361-694-5311
Driscoll Children's Hospital Driscoll Children's Hospital was built because Clara Driscoll's will requested that a...
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1200 Pleasant Street
Des Moines, Iowa 50309
Des Moines, Iowa 50309
(515) 241-KIDS
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Principal Investigator: Wendy L. Woods-Swafford
Phone: 515-241-6729
Blank Children's Hospital Blank Children's Hospital is completely dedicated to meeting the unique health care...
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1500 E Duarte Rd
Duarte, California 91010
Duarte, California 91010
(626) 256-4673
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Principal Investigator: Anna B. Pawlowska
Phone: 800-826-4673
City of Hope Comprehensive Cancer Center City of Hope is a leading research and treatment...
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3300 Gallows Road
Falls Church, Virginia 22042
Falls Church, Virginia 22042
(703) 776-4001
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Principal Investigator: Marshall A. Schorin
Phone: 703-208-6650
Inova Fairfax Hospital Inova Fairfax Hospital, Inova's flagship hospital, is an 833-bed, nationally recognized regional...
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1 Hurley Plaza
Flint, Michigan 48503
Flint, Michigan 48503
(810) 262-9000
![Hurley Medical Center](/wp-content/uploads/logos/hurley-medical-center.png)
Principal Investigator: Susumu Inoue
Phone: 888-606-6556
Hurley Medical Center From its founding in 1908, Hurley Medical Center has devoted itself to...
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Lee Memorial Health System Our origins can be traced to the Fall of 1916 when...
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Brooke Army Medical Center Brooke Army Medical Center (BAMC) is the Flagship of Army Medicine!...
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100 Michigan Street Northeast
Grand Rapids, Michigan 49503
Grand Rapids, Michigan 49503
616.391.9000
![Helen DeVos Children's Hospital at Spectrum Health](/wp-content/uploads/logos/helen-devos-children-s-hospital-at-spectrum-health.png)
Principal Investigator: David S. Dickens
Phone: 616-267-1925
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282 Washington St
Hartford, Connecticut 06106
Hartford, Connecticut 06106
(860) 545-9000
![Connecticut Children's Medical Center](/wp-content/uploads/logos/connecticut-children-s-medical-center.jpg)
Principal Investigator: Michael S. Isakoff
Phone: 860-545-9981
Connecticut Children's Medical Center Connecticut Children’s Medical Center is a nationally recognized, 187-bed not-for-profit children’s...
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2500 N State St
Jackson, Mississippi 39216
Jackson, Mississippi 39216
(601) 984-1000
![University of Mississippi Medical Center](/wp-content/uploads/logos/university-of-mississippi-medical-center.png)
Principal Investigator: Gail C. Megason
Phone: 601-815-6700
University of Mississippi Medical Center The University of Mississippi Medical Center, located in Jackson, is...
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524 South Park Street
Kalamazoo, Michigan 49007
Kalamazoo, Michigan 49007
(269) 341-7654
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Principal Investigator: Katharina E. Elliott
Phone: 616-391-1230
Bronson Methodist Hospital Our healthcare system serves patients and families throughout southwest Michigan and northern...
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1800 West Charleston Boulevard
Las Vegas, Nevada 89102
Las Vegas, Nevada 89102
(702) 383-2000
![University Medical Center of Southern Nevada](/wp-content/uploads/logos/university-medical-center-of-southern-nevada.jpg)
Principal Investigator: Alan K. Ikeda
Phone: 702-384-0013
University Medical Center of Southern Nevada University Medical Center is dedicated to providing the highest...
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529 West Markham Street
Little Rock, Arkansas 72205
Little Rock, Arkansas 72205
(501) 686-7000
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University of Arkansas for Medical Sciences The University of Arkansas for Medical Sciences (UAMS) in...
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4650 Sunset Blvd
Los Angeles, California 90027
Los Angeles, California 90027
(323) 660-2450
![Childrens Hospital Los Angeles](/wp-content/uploads/logos/childrens-hospital-los-angeles.jpg)
Principal Investigator: Leo Mascarenhas
Phone: 323-361-4110
Childrens Hospital Los Angeles Children's Hospital Los Angeles is a 501(c)(3) nonprofit hospital for pediatric...
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8700 Beverly Blvd # 8211
Los Angeles, California 90048
Los Angeles, California 90048
(1-800-233-2771)
![Cedars-Sinai Medical Center](/wp-content/uploads/logos/cedars-sinai-med-ctr.png)
Principal Investigator: Fataneh (Fae) Majlessipour
Phone: 310-423-8965
Cedars Sinai Med Ctr Cedars-Sinai is known for providing the highest quality patient care. Our...
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4015 22nd Place
Lubbock, Texas 79410
Lubbock, Texas 79410
806-725-0000
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Principal Investigator: Kishor M. Bhende
Phone: 806-725-8000
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262 Danny Thomas Pl
Memphis, Tennessee 38105
Memphis, Tennessee 38105
(901) 495-3300
![St. Jude Children's Research Hospital](/wp-content/uploads/logos/st-jude-children-s-research-hospital.png)
Principal Investigator: Wayne L. Furman
Phone: 901-595-4644
St. Jude Children's Research Hospital St. Jude is unlike any other pediatric treatment and research...
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601 Children's Lane
Norfolk, Virginia 23507
Norfolk, Virginia 23507
(757) 668-7000
![Children's Hospital of The King's Daughters](/wp-content/uploads/logos/children-s-hospital-of-the-king-s-daughters.gif)
Principal Investigator: Eric J. Lowe
Phone: 757-668-7243
Children's Hospital of The King's Daughters Children
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747 52nd St
Oakland, California 94609
Oakland, California 94609
(510) 428-3000
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Principal Investigator: Carla B. Golden
Phone: 510-450-7600
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1201 W La Veta Ave
Orange, California 92868
Orange, California 92868
(714) 997-3000
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Principal Investigator: Elyssa M. Rubin
Phone: 714-997-3000
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1717 South Orange Avenue # 100
Orlando, Florida 32806
Orlando, Florida 32806
(407) 650-7000
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Nemours Children's Clinic - Orlando Located near downtown Orlando, Nemours Children’s Clinic, Orlando is a...
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5153 North 9th Avenue
Pensacola, Florida 32504
Pensacola, Florida 32504
(850) 505-4700
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Principal Investigator: Jeffrey H. Schwartz
Phone: 904-697-3529
Nemours Children's Clinic - Pensacola Nemours Children’s Clinic, Pensacola serves children and families in northwest...
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530 Northeast Glen Oak Avenue
Peoria, Illinois 61603
Peoria, Illinois 61603
(309) 624-4945
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Principal Investigator: Pedro A. De Alarcon
Phone: 888-226-4343
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South 34th Street
Philadelphia, Pennsylvania 19104
Philadelphia, Pennsylvania 19104
215-590-1000
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Principal Investigator: Frank M. Balis
Phone: 215-590-2810
Children's Hospital of Philadelphia Since its start in 1855 as the nation's first hospital devoted...
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4401 Penn Avenue
Pittsburgh, Pennsylvania 15224
Pittsburgh, Pennsylvania 15224
412-692-5325
![Children's Hospital of Pittsburgh of UPMC](/wp-content/uploads/logos/children-s-hospital-of-pittsburgh-of-upmc.jpg)
Principal Investigator: Arthur K. Ritchey
Phone: 412-692-5573
Children's Hospital of Pittsburgh of UPMC UPMC is one of the leading nonprofit health systems...
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3181 Southwest Sam Jackson Park Road
Portland, Oregon 97239
Portland, Oregon 97239
503 494-8311
![Oregon Health and Science University](/wp-content/uploads/logos/oregon-health-and-science-university.jpg)
Principal Investigator: Linda C. Stork
Phone: 503-494-1080
Oregon Health and Science University In 1887, the inaugural class of the University of Oregon...
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620 John Paul Jones Cir
Portsmouth, Virginia 23708
Portsmouth, Virginia 23708
(757) 953-5008
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Principal Investigator: Bethany M. Mikles
Phone: 757-953-5939
Naval Medical Center - Portsmouth Naval Medical Center Portsmouth, Virginia has proudly served the military...
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593 Eddy Street
Providence, Rhode Island 02903
Providence, Rhode Island 02903
401-444-4000
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Principal Investigator: Jennifer J. Greene Welch
Phone: 401-444-1488
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401 College Street
Richmond, Virginia 23298
Richmond, Virginia 23298
(804) 828-0450
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Principal Investigator: Madhu S. Gowda
Virginia Commonwealth University Massey Cancer Center Founded in 1974, VCU Massey Cancer Center is a...
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60 Crittenden Blvd # 70
Rochester, New York 14642
Rochester, New York 14642
(585) 275-2121
![University of Rochester](/wp-content/uploads/logos/university-of-rochester.png)
Principal Investigator: Angela R. Girvin
Phone: 585-275-5830
University of Rochester The University of Rochester is one of the country's top-tier research universities....
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7700 Floyd Curl Dr
San Antonio, Texas 78229
San Antonio, Texas 78229
(210) 575-7000
![Methodist Children's Hospital of South Texas](/wp-content/uploads/logos/methodist-children-s-hospital-of-south-texas.png)
Principal Investigator: Vinod K. Gidvani-Diaz
Phone: 210-575-7000
Methodist Children's Hospital of South Texas Methodist Children
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4502 Medical Drive
San Antonio, Texas 78284
San Antonio, Texas 78284
(210) 567-7000
![University of Texas Health Science Center at San Antonio](/wp-content/uploads/logos/university-of-texas-health-science-center-at-san-antonio.jpg)
Principal Investigator: Anne-Marie R. Langevin
Phone: 210-450-3800
University of Texas Health Science Center at San Antonio The University of Texas Health Science...
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3020 Childrens way
San Diego, California 92123
San Diego, California 92123
(858) 576-1700
![Rady Children's Hospital - San Diego](/wp-content/uploads/logos/rady-children-s-hospital---san-diego.jpg)
Principal Investigator: William D. Roberts
Phone: 858-966-5934
Rady Children's Hospital - San Diego Rady Children's Hospital-San Diego is the region’s pediatric medical...
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34800 Bob Wilson Dr,
San Diego, California 92134
San Diego, California 92134
(619) 532-6400
![Naval Medical Center - San Diego](/wp-content/uploads/logos/naval-medical-center---san-diego.png)
Principal Investigator: Yoko T. Udaka
Phone: 619-532-8712
Naval Medical Center - San Diego We are the largest and most comprehensive military healthcare...
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Tampa General Hospital In a diverse city known for its rich culture and beautiful beaches,...
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40 Sunshine Cottage Road
Valhalla, New York 10595
Valhalla, New York 10595
(914) 594-4000
![New York Medical College](/wp-content/uploads/logos/new-york-medical-college.jpg)
Principal Investigator: Jessica C. Hochberg
Phone: 914-594-3794
New York Medical College The College was founded in 1860 by a group of New...
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1600 Rockland Road
Wilmington, Delaware 19803
Wilmington, Delaware 19803
(302) 651-4200
![Alfred I. duPont Hospital for Children](/wp-content/uploads/logos/alfred-i-dupont-hospital-for-children.jpg)
Principal Investigator: Ramamoorthy Nagasubramanian
Phone: 302-651-6884
Alfred I. duPont Hospital for Children Nemours began more than 70 years ago with the...
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Akron, Ohio 44308
Principal Investigator: Steven J. Kuerbitz
Phone: 330-543-3193
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Albany, New York 12208
Principal Investigator: Kenneth G. Lucas
Phone: 518-262-5513
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Anchorage, Alaska 99508
Principal Investigator: Brenda J. Wittman
Phone: 907-212-6871
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1540 East Hospital Drive
Ann Arbor, Michigan 48109
Ann Arbor, Michigan 48109
(877) 475-6688
![C S Mott Children's Hospital](/wp-content/uploads/logos/c-s-mott-children-s-hospital.jpg)
Principal Investigator: Raymond J. Hutchinson
Phone: 800-865-1125
C S Mott Children's Hospital Behind the doors of C.S. Mott Children's Hospital there exist...
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Asheville, North Carolina 28801
Principal Investigator: Douglas J. Scothorn
Phone: 828-213-4150
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Atlanta, Georgia 30322
Principal Investigator: Bradley A. George
Phone: 404-785-1112
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Augusta, Georgia 30912
Principal Investigator: Colleen H. McDonough
Phone: 706-721-2388
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13123 E 16th Ave
Aurora, Colorado 80045
Aurora, Colorado 80045
(720) 777-1234
![Children's Hospital Colorado](/wp-content/uploads/logos/children-s-hospital-colorado.jpg)
Principal Investigator: Timothy P. Garrington
Phone: 720-777-6672
Children's Hospital Colorado At Children's Hospital Colorado, we see more, treat more and heal more...
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22 South Greene Street
Baltimore, Maryland 21201
Baltimore, Maryland 21201
410-328-7904
![University of Maryland Greenebaum Cancer Center](/wp-content/uploads/logos/university-of-maryland-greenebaum-cancer-center.jpg)
Principal Investigator: Teresa A. York
Phone: 800-888-8823
University of Maryland Greenebaum Cancer Center The University of Maryland Marlene and Stewart Greenebaum Cancer...
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2401 W Belvedere Ave
Baltimore, Maryland 21215
Baltimore, Maryland 21215
(410) 601-9000
![Sinai Hospital of Baltimore](/wp-content/uploads/logos/sinai-hospital-of-baltimore.jpg)
Principal Investigator: Jason M. Fixler
Phone: 410-601-6120
Sinai Hospital of Baltimore Sinai Hospital of Baltimore provides a broad array of high-quality, cost-effective...
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401 North Broadway
Baltimore, Maryland 21287
Baltimore, Maryland 21287
410-955-5000
![Johns Hopkins University-Sidney Kimmel Cancer Center](/wp-content/uploads/logos/johns-hopkins-university-sidney-kimmel-cancer-center.png)
Principal Investigator: Alan D. Friedman
Phone: 410-955-8804
Johns Hopkins University-Sidney Kimmel Cancer Center The name Johns Hopkins has become synonymous with excellence...
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489 State St
Bangor, Maine 04401
Bangor, Maine 04401
(207) 973-7000
![Eastern Maine Medical Center](/wp-content/uploads/logos/eastern-maine-medical-center.png)
Principal Investigator: Nadine P. SantaCruz
Phone: 207-973-4274
Eastern Maine Medical Center Located in Bangor, Eastern Maine Medical Center (EMMC) serves communities throughout...
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8901 Rockville Pike
Bethesda, Maryland 20889
Bethesda, Maryland 20889
(301) 295-4000
![Walter Reed National Military Medical Center](/wp-content/uploads/logos/walter-reed-national-military-medical-center.jpg)
Principal Investigator: Kenneth Lieuw
Phone: 301-319-2100
Walter Reed National Military Medical Center The Walter Reed National Military Medical Center is one...
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100 E Idaho St
Boise, Idaho 83712
Boise, Idaho 83712
(208) 381-2711
![Saint Luke's Mountain States Tumor Institute](/wp-content/uploads/logos/saint-luke-s-mountain-states-tumor-institute.gif)
Principal Investigator: Eugenia Chang
Phone: 800-845-4624
Saint Luke's Mountain States Tumor Institute For more than 100 years, St. Luke
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Boston, Massachusetts 02111
Principal Investigator: Michael J. Kelly
Phone: 617-636-5535
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55 Fruit St
Boston, Massachusetts 02114
Boston, Massachusetts 02114
(617) 724-4000
![Massachusetts General Hospital Cancer Center](/wp-content/uploads/logos/massachusetts-general-hospital-cancer-center.jpg)
Principal Investigator: Alison M. Friedmann
Phone: 877-726-5130
Massachusetts General Hospital Cancer Center An integral part of one of the world
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450 Brookline Ave
Boston, Massachusetts 2215
Boston, Massachusetts 2215
617-632-3000
![Dana-Farber Cancer Institute](/wp-content/uploads/logos/dana-farber-cancer-institute.gif)
Principal Investigator: Suzanne Shusterman
Phone: 877-442-3324
Dana-Farber Cancer Institute Since it’s founding in 1947, Dana-Farber has been committed to providing adults...
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Bronx, New York 10467
Principal Investigator: Lisa Gennarini
Phone: 718-379-6866
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Brooklyn Hospital Center Welcome to The Brooklyn Hospital Center, dedicated to Keeping Brooklyn healthy and...
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Chapel Hill, North Carolina 27599
Principal Investigator: Stuart H. Gold
Phone: 877-668-0683
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171 Ashley Avenue
Charleston, South Carolina 29425
Charleston, South Carolina 29425
843-792-1414
![Medical University of South Carolina](/wp-content/uploads/logos/medical-university-of-south-carolina.jpg)
Principal Investigator: Jacqueline M. Kraveka
Phone: 843-792-9321
Medical University of South Carolina The Medical University of South Carolina (MUSC) has grown from...
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3110 MacCorkle Avenue Southeast
Charleston, West Virginia 25304
Charleston, West Virginia 25304
Principal Investigator: Ashley E. Meyer
Phone: 304-388-9944
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Charlotte, North Carolina 28204
Principal Investigator: Jessica A. Bell
Phone: 704-384-5369
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Charlotte, North Carolina 28204
Principal Investigator: Joel A. Kaplan
Phone: 800-804-9376
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Chattanooga, Tennessee 37403
Principal Investigator: Manoo G. Bhakta
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Chicago, Illinois 60614
Principal Investigator: Amy L. Walz
Phone: 773-880-4562
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1200 West Harrison Stree
Chicago, Illinois 60607
Chicago, Illinois 60607
(312) 996-4350
![Univ of Illinois](/wp-content/uploads/logos/univ-of-illinois.jpg)
Principal Investigator: Mary L. Schmidt
Phone: 312-355-3046
Univ of Illinois A major research university in the heart of one of the world's...
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5841 S Maryland Ave
Chicago, Illinois 60637
Chicago, Illinois 60637
1-773-702-6180
![University of Chicago Comprehensive Cancer Center](/wp-content/uploads/logos/university-of-chicago-comprehensive-cancer-center.png)
Principal Investigator: Susan L. Cohn
Phone: 773-702-8222
University of Chicago Comprehensive Cancer Center The University of Chicago Comprehensive Cancer Center (UCCCC) is...
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2049 E 100th St
Cleveland, Ohio 44106
Cleveland, Ohio 44106
(216) 444-2200
![Cleveland Clinic Foundation](/wp-content/uploads/logos/cleveland-clinic-foundation.jpg)
Principal Investigator: Rabi Hanna
Phone: 866-223-8100
Cleveland Clinic Foundation The Cleveland Clinic (formally known as The Cleveland Clinic Foundation) is a...
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Columbia, Missouri 65201
Principal Investigator: Barbara A. Gruner
Phone: 573-882-7440
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5 Richland Medical Park Dr
Columbia, South Carolina 29203
Columbia, South Carolina 29203
(803) 434-7000
![Palmetto Health Richland](/wp-content/uploads/logos/palmetto-health-richland.png)
Principal Investigator: Stuart L. Cramer
Phone: 803-434-3680
Palmetto Health Richland Palmetto Health Richland, originally founded in 1892 as Columbia Hospital, has a...
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Dallas, Texas 75390
Principal Investigator: Jonathan E. Wickiser
Phone: 214-648-7097
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100 North Academy Avenue
Danville, Pennsylvania 17822
Danville, Pennsylvania 17822
570-271-6211
![Geisinger Medical Center](/wp-content/uploads/logos/geisinger-medical-center.jpg)
Principal Investigator: Jagadeesh Ramdas
Phone: 570-271-5251
Geisinger Medical Center Since 1915, Geisinger Medical Center has been known as the region’s resource...
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Dayton, Ohio 45404
Principal Investigator: Ayman A. El-Sheikh
Phone: 800-228-4055
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Denver, Colorado 80218
Principal Investigator: Jennifer J. Clark
Phone: 866-775-6246
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4160 John R St #2122
Detroit, Michigan 48201
Detroit, Michigan 48201
(313) 833-1785
![Wayne State University/Karmanos Cancer Institute](/wp-content/uploads/logos/wayne-state-university-karmanos-cancer-institute.png)
Principal Investigator: Sureyya Savasan
Phone: 313-576-9363
Wayne State University/Karmanos Cancer Institute Karmanos is based in southeast Michigan, in midtown Detroit, and...
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Detroit, Michigan 48236
Principal Investigator: Adonis N. Lorenzana
Phone: 734-712-3671
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9333 Imperial Highway
Downey, California 90242
Downey, California 90242
Principal Investigator: Robert M. Cooper
Phone: 510-891-3400
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2301 Erwin Rd
Durham, North Carolina 27710
Durham, North Carolina 27710
919-684-8111
![Duke Univ Med Ctr](/wp-content/uploads/logos/duke-univ-med-ctr.png)
Principal Investigator: Susan G. Kreissman
Phone: 888-275-3853
Duke Univ Med Ctr As a world-class academic and health care system, Duke Medicine strives...
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East Lansing, Michigan 48824
Principal Investigator: Aghiad Chamdin
Phone: 517-975-9547
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801 Broadway North
Fargo, North Dakota 58122
Fargo, North Dakota 58122
Principal Investigator: Samuel O. Anim
Phone: 800-437-4010
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1600 S Andrews Ave
Fort Lauderdale, Florida 33316
Fort Lauderdale, Florida 33316
(954) 355-4400
![Broward Health Medical Center](/wp-content/uploads/logos/broward-health-medical-center.png)
Principal Investigator: Hector M. Rodriguez-Cortes
Phone: 954-355-5346
Broward Health Medical Center Broward Health, providing service for more than 75 years, is a...
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Fort Myers, Florida 33908
Principal Investigator: Emad K. Salman
Phone: 239-343-5333
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801 7th Avenue
Fort Worth, Texas 76104
Fort Worth, Texas 76104
(682) 885-4000
![Cook Children's Medical Center](/wp-content/uploads/logos/cook-children-s-medical-center.png)
Principal Investigator: Kelly L. Vallance
Phone: 682-885-2103
Cook Children's Medical Center Cook Children's Health Care System is a not-for-profit, nationally recognized pediatric...
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1600 Southwest Archer Road
Gainesville, Florida 32610
Gainesville, Florida 32610
Principal Investigator: William B. Slayton
Phone: 352-273-8010
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835 S Van Buren St
Green Bay, Wisconsin 54301
Green Bay, Wisconsin 54301
Principal Investigator: Catherine A. Long
Phone: 920-433-8889
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1001 E 5th St
Greenville, North Carolina 27858
Greenville, North Carolina 27858
(252) 328-6131
![East Carolina University](/wp-content/uploads/logos/east-carolina-university.jpg)
Principal Investigator: Andrea R. Whitfield
Phone: 252-744-1015
East Carolina University Whether it's meeting the demand for more teachers and healthcare professionals or...
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900 West Faris Rd.
Greenville, South Carolina 29605
Greenville, South Carolina 29605
(864)455-8898
![BI-LO Charities Children's Cancer Center](/wp-content/uploads/logos/bi-lo-charities-children-s-cancer-center.jpg)
Principal Investigator: Nichole L. Bryant
Phone: 864-241-6251
BI-LO Charities Children's Cancer Center The BI-LO Charities Children
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Greenville, South Carolina 29605
Principal Investigator: Cary E. Stroud
Phone: 864-241-6251
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30 Prospect Ave
Hackensack, New Jersey 07601
Hackensack, New Jersey 07601
(201) 996-2000
![Hackensack University Medical Center](/wp-content/uploads/logos/hackensack-university-medical-center.jpg)
Principal Investigator: Burton E. Appel
Phone: 201-996-2879
Hackensack University Medical Center Hackensack University Medical Center, part of the Hackensack University Health Network,...
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