Study of Angiogenesis Proteins and Tumor Markers in Inflammatory Breast Cancer Tissue Samples
| Status: | Archived |
|---|---|
| Conditions: | Breast Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
Evaluation of Angiogenesis Parameters and Tumor Markers in Inflammatory Breast Cancer Specimens
RATIONALE: Studying samples of tumor tissue from patients with cancer in the laboratory may
help doctors learn more about changes that may occur in DNA, identify biomarkers related to
cancer, and identify proteins involved in forming tumor blood vessels. It may also help in
the diagnosis of inflammatory breast cancer.
PURPOSE: This laboratory study is looking at angiogenesis proteins and tumor markers in
inflammatory breast cancer tissue samples.
OBJECTIVES:
- Examine breast tissue from patients with inflammatory breast cancer for tumor markers
and factors associated with angiogenesis.
OUTLINE: Tissue specimens are obtained from the George Washington University Inflammatory
Breast Cancer Registry and Biospecimen Repository. Specimens are tested for biological
markers (such as estrogen receptor, progesterone receptor, the p53 gene, and others) and
angiogenesis parameters (such as various proteins involved in vessel formation) to determine
their prevalence in these specimens and to help in the classification of breast tumors.
PROJECTED ACCRUAL: A total of 300 tissue specimens from patients will accrued for this
study.
We found this trial at
2
sites
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National Cancer Institute (NCI) The National Cancer Institute (NCI) is part of the National Institutes...
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