The Effects of One-Time Pregnenolone, Dehydroepiandrosterone (DHEA), or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers
| Status: | Archived |
|---|---|
| Conditions: | Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | July 2009 |
| End Date: | January 2011 |
The Effects of One-Time Pregnenolone, DHEA, Or Placebo Administration On Withdrawal Symptoms, Mood, Craving And Cigarette Evaluation Ratings In Male Smokers
This study will evaluate the potential therapeutic value of two neurosteroid treatments
(DHEA and pregnenolone) in the treatment of tobacco withdrawal symptoms. This will include
assessing whether these agents relieve craving for cigarettes elicited by exposure to a
mildly stressful cognitive task. Pregnenolone (400 mg orally), DHEA (400 mg orally) and
placebo will be administered one at each of the three sessions in a randomized order.
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