Determining When Patients Hospitalized With Acute Heart Failure Can Be Safely Sent Home (The DECIDE Study)



Status:Completed
Conditions:Cardiology
Therapuetic Areas:Cardiology / Vascular Diseases
Healthy:No
Age Range:18 - Any
Updated:10/2/2013
Start Date:August 2008
End Date:June 2011
Contact:Sue Roll, RN
Phone:513-558-6061

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Treatment Endpoints in Acute Decompensated Heart Failure


The purpose of this study is to determine if certain findings (blood tests, symptom
improvement, etc.) after acute heart failure treatment can identify a group of patients who
are safe for early hospital discharge.


A fundamental question faced by physicians treating acute decompensated heart failure (ADHF)
is "When has treatment worked sufficiently for safe discharge, and who requires further
treatment?" Patients with ADHF have a high incidence of morbidity and mortality. Current
guidelines for emergency department (ED) and hospital disposition of patients with ADHF are
based on limited empirical evidence. This creates clinical uncertainty regarding disposition
leads to prolonged hospitalizations, higher costs and increased resource consumption. The
specific aim of the study is to develop a prediction rule from readily available clinical
data to help physicians identify ADHF patients eligible for safe and early discharge from
the ED and hospital after treatment is initiated.

Inclusion Criteria:

- Fulfill the modified Framingham criteria

- Have baseline data available within 1 hour of initial ED therapy

- Have previously documented systolic dysfunction (ejection fraction less than 50%) by
echocardiogram

- Willing and able to give informed consent
We found this trial at
2
sites
2600 Clifton Ave
Cincinnati, Ohio 45267
(513) 556-6000
University of Cincinnati The University of Cincinnati offers students a balance of educational excellence and...
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2201 West End Ave
Nashville, Tennessee 37232
(615) 322-7311
Vanderbilt University Vanderbilt offers undergraduate programs in the liberal arts and sciences, engineering, music, education...
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Nashville, TN
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