Biospecimen Repository for Cardiac Arrhythmias at the Cleveland Clinic

The long-term objective of this research is to find genes and biologic pathways causing
arrhythmia syndromes and other diseases or conditions. In order to achieve this objective the
investigators will collect comprehensive phenotypic data and corresponding blood and/or
tissue samples into a biorepository registry of patients, presenting for cardiac arrhythmia
evaluation and/or treatment, and control subjects without arrhythmias. This biorepository
will be composed of two parts: 1) An Arrhythmia Biorepository of blood and tissue from
patients undergoing arrhythmia procedures, cardiac surgery, or inpatient or outpatient
evaluations for arrhythmias, and 2) A Collaborative Sample Biorepository for de-identified
samples and data from outside institutions and clinical trials.

Inclusion Criteria:

- Male or female at least 18 years old

- Subjects with a history of or current cardiac arrhythmia, family members of subjects
with cardiac arrhythmias, or no cardiac arrhythmia if a Control Subject.

Exclusion Criteria:

- Subjects previously enrolled in the Arrhythmia BioBank