Study of Anatomic Nerve Sparing Radical Perineal Prostatectomy

The purpose of our study is to evaluate perioperative, oncologic, and functional outcomes for
the anatomic radical perineal prostatectomy. The anatomic radical perineal prostatectomy is
standard-of-care surgical approach to the surgical management of localized prostate cancer.
The operative technique selected for radical prostatectomy is largely based on patient
preference after appropriate counseling, and surgeon recommendation based on surgical
considerations and surgeon experience. Outcome data for the anatomic radical perineal
prostatectomy will represent a valuable addition to the published body of literature. Our
study is a prospective clinical outcome data collection and analysis and we will be looking
at data within several domains. First, perioperative data will be collected to evaluate the
OR time, blood loss, surgical complications, and length of hospital stay for the anatomic
radical perineal prostatectomy. Second, oncologic efficacy of this procedure will be
reported, based on margin status of surgical specimens, which will be correlated with tumor
features (Gleason score, tumor volume, pre-op PSA score). Third, functional outcomes will be
evaluated by comparing urinary, sexual, and bowel function in the pre-op and post-op
settings. This third domain will be accomplished by employing the following validated
questionnaires (attached - SHIM, IPSS, and EPIC-26). These questionnaires will be filled out
at 3 time-points: pre-op, and at 3 months and 12 months post-operatively.

Inclusion Criteria:

- 18 years of age

- Perineal prostatectomy for prostate cancer at Maimonides Medical Center

Exclusion Criteria:

- Dementia