Decreasing Dialysis Cardiovascular Risk: Daily Versus Longer Treatments
| Status: | Recruiting |
|---|---|
| Conditions: | Peripheral Vascular Disease |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 21 - Any |
| Updated: | 4/2/2016 |
| Start Date: | August 2004 |
| Contact: | Devasmita C. Dev, MD |
| Email: | Devasmita.dev@med.va.gov |
| Phone: | 214-857-1593 |
Given the known increased risk of heart disease in hemodialysis patients, this study aims to
evaluate the change in both size and function of the heart by using cardiac magnetic
resonance imaging (MRI) in patients undergoing either daily long (4 hours, 6 times weekly),
daily short (2 hours 6 times weekly), or alternate day conventional (4 hours, 3 times
weekly) and alternate day long (8 hours, 3 times weekly) dialysis for 6 months from
randomization. The patients are randomly put in the groups based on predetermined
randomization schedule and the cardiologist trained in cardiac MRI readings is blinded to
the patient treatment schedule. Given that changes in heart function may be seen with
cardiac imaging techniques within 6 months, the expectation is that groups on daily
treatment may have better outcome for this parameter as changes in volume and blood pressure
may also be affected in a positive way in patients on daily dialysis.
evaluate the change in both size and function of the heart by using cardiac magnetic
resonance imaging (MRI) in patients undergoing either daily long (4 hours, 6 times weekly),
daily short (2 hours 6 times weekly), or alternate day conventional (4 hours, 3 times
weekly) and alternate day long (8 hours, 3 times weekly) dialysis for 6 months from
randomization. The patients are randomly put in the groups based on predetermined
randomization schedule and the cardiologist trained in cardiac MRI readings is blinded to
the patient treatment schedule. Given that changes in heart function may be seen with
cardiac imaging techniques within 6 months, the expectation is that groups on daily
treatment may have better outcome for this parameter as changes in volume and blood pressure
may also be affected in a positive way in patients on daily dialysis.
Inclusion Criteria:
- End stage renal disease patients on hemodialysis
Exclusion Criteria:
- Weight > 350 lbs
- Known poor dialysis and or treatment compliance
- Unable to come for daily treatments if randomization occurs in this group
- Prognosis less than 6 months
- Difficulty in tolerating dialysis and possibility of discontinuation of dialysis
before 6 months
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Dallas VA Medical Center VA North Texas Health Care System (VANTHCS) is a progressive health...
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