A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma



Status:Archived
Conditions:Skin and Soft Tissue Infections, Dermatology
Therapuetic Areas:Dermatology / Plastic Surgery
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:September 2009
End Date:September 2011

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Trial Summary
Trial Overview
Inclusion Criteria

A Phase 1 Multicenter, Open-label Study to Evaluate the Safety and Tolerability of Single and Multiple Intravenous Doses of MEDI-546, a Fully Human Monoclonal Antibody Directed Against Subunit 1 of the Type I Interferon Receptor, in Adult Subjects With Scleroderma


To evaluate the safety and tolerability of a multiple-dosed drug (MEDI-546) in adults with
scleroderma.


The primary objective of this study is to evaluate the safety and tolerability of single and
multiple IV doses of MEDI-546 in adult subjects with scleroderma who have skin thickening in
an area suitable for repeat biopsy.


We found this trial at
11
sites
David Geffen School of Medicine, UCLA
10833 Le Conte Ave
Los Angeles, California 90095
(310) 825-4321
David Geffen School of Medicine, UCLA In 2002 Mr. David Geffen announced a $200 million...
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University of Michigan Health Systems
1500 E Medical Center Dr
Ann Arbor, Michigan 48109
(734) 936-4000
University of Michigan Health Systems The University of Michigan is home to one of the...
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Ann Arbor, MI
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Boston Med Center
1 Boston Medical Center Pl
Boston, Massachusetts 02118
617.638.8000
Boston Med Center Boston Medical Center (BMC) is a 496-bed academic medical center located in...
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Boston, MA
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Metroplex Clinical Research Center
8144 Walnut Hill Lane
Northeast, Texas 75231
214-879-6737
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Northeast, TX
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Georgetown Univ Med Ctr
4000 Reservoir Road NW, Suite 120
Washington, Washington DC 20007
(202) 687-0100
Georgetown Univ Med Ctr Georgetown University Medical Center is committed to excellence in research, education...
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Washington, DC
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Houston Medical School
Houston, Texas 77030
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Houston, TX
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North Shore - Long Island Jewish Health System
Lake Success, New York 11042
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Lake Success, NY
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University of Medicine and Dentistry - Robert Wood Johnson University Hospital
New Brunswick, New Jersey 08903
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New Brunswick, NJ
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University Of Utah Hospital
Salt Lake City, Utah 84132
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Salt Lake City, UT
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Virginia Mason Medical Center
Seattle, Washington 98101
(888) 862-2737
Virginia Mason Medical Center Established in 1920, Virginia Mason began as an 80-bed hospital with...
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Seattle, WA
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University of Toledo Medical Center
Toledo, Ohio 43614
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Toledo, OH
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