Atkins Diet and Prostate Cancer Clinical Trial

Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer.
While a very effective anti-cancer treatment, ADT is associated with significant toxicity
including but not limited to major metabolic disturbances including impaired glucose
tolerance, insulin resistance, and weight gain. We hypothesize that limiting carbohydrates
within the diet will prevent or at least minimize these consequences.

Inclusion Criteria:

1. Histologically confirmed adenocarcinoma of the prostate

2. Scheduled to initiate ADT with an anticipated duration of ≥ 6 months

3. Overweight or obese (body mass index ≥ 25 kg/m2)

Exclusion Criteria:

1. Symptomatic metastatic disease

2. Myocardial infarction within 6 months

3. Treatment with medications known to affect insulin or glucose levels (i.e. insulin,
oral hypoglycemics, prednisone, etc.)

4. Patient consuming a low-carbohydrate diet

5. Medical conditions or co-morbidities that preclude participation in the protocol

6. Vegetarians