Vascular Inflammation in Adolescents With Type 1 Diabetes
| Status: | Archived |
|---|---|
| Conditions: | Peripheral Vascular Disease, Cardiology, Diabetes |
| Therapuetic Areas: | Cardiology / Vascular Diseases, Endocrinology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
| Start Date: | January 2010 |
Prevalence of Oxidative Stress, Endothelial Dysfunction, Increased Carotid Artery Intima-media Thickness (cIMT) and Biomarkers of Vascular Inflammation in Adolescents With Type-1 Diabetes Mellitus (T1DM)
The purpose of this study is to find out if diabetes damages the blood vessels of
adolescents with good diabetes control compared to adolescents with less optimal control.
Many published studies reveal that adult patients with T1DM can have early, silent and more
advanced vessel wall thickness than normal subjects. This is influenced by the degree of
their blood sugar control. If this is happening in adolescents, we want to know what
proportion of adolescent children with type 1 diabetes show signs of early blood vessel
damage. We also want to learn if these signs of damage are linked to other factors such as
how long someone has had diabetes, blood sugar control or individual differences because of
a difference in genetic make-up.
We found this trial at
1
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