CT Coronary Angiogram Versus Traditional Care in Emergency Department Assessment of Potential ACS

In this study, participants with potential ACS will be randomized to traditional "rule out"
care (Group A) or to traditional care plus CT coronary angiography (Group B) in a ratio of
1:2 traditional versus traditional plus CT coronary angiography.

In Group A, all management and disposition decisions will be made by the healthcare
providers caring for the participant. Participants will be admitted to hospital, admitted to
cardiac diagnostic unit, or discharged to home. Diagnostic testing and treatment will be
decided by the team caring for the participant. Follow up will comprise telephone interviews
at 30 days and 1 year later.

In Group B, participants will receive initial cardiac troponin and creatinine blood tests.
Upon return of normal laboratory values, the participants will receive a CT coronary
angiography an estimated 90 minutes after the initial values assessment or as soon as the CT
scanner is available. Participants with negative test results will be discharged; follow up
will comprise telephone interviews at 30 days and 1 year later. Participants with positive
test results will be admitted to the hospital for further management dictated by the
admitting team.