Facilitating Parent Adaptation to Pediatric Transplant: The P-SCIP Trial

The investigators have developed a parent social-cognitive processing intervention (P-SCIP)
to help decrease distress among parent caregivers of children undergoing hematopoietic stem
cell transplant (HSCT). The investigators will evaluate the efficacy of P-SCIP in reducing
short- and long-term distress and parenting stress among 300 parents of children undergoing
HSCT. P-SCIP will be delivered during the child's inpatient HSCT hospitalization and is
specifically designed to improve parent social (e.g., sharing concerns) and cognitive (e.g.,
acceptance) processing of the transplant experience. The intervention includes five
in-person sessions that are accompanied by an interactive CD-ROM. The CD-ROM complements the
materials in the in-person sessions and provides parents with the opportunity to enhance and
deepen their cognitive and social processing of the HSCT experience. The intervention will
be tested against best-practices psychosocial care (BPC) available in four enriched
pediatric HSCT settings across the United States. P-SCIP will be provided to both Spanish-
and English-speaking parents. Participants will complete measures of psychological distress,
well-being, and social and cognitive processing at the time of HSCT, two, six and twelve
months after HSCT. Research questions will address the effects of P-SCIP versus BPC on
parent psychological adaptation and social and cognitive processing, as well as evaluate
parent personal resources as well as child medical course variables that contribute to
intervention response. The investigators will also examine barriers to participation in the
intervention by comparing barriers to participation among parents who refuse participation
in the trial and parents who accept.