Minor Histocompatibility Vaccination After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies



Status:Archived
Conditions:Blood Cancer, Lymphoma, Orthopedic, Hematology
Therapuetic Areas:Hematology, Oncology, Orthopedics / Podiatry
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:May 2003
End Date:December 2013

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A Phase I/II Study of Vaccination Against Minor Histocompatibility Antigens HA1 or HA2 After Allogeneic Stem Cell Transplantation for Advanced Hematologic Malignancies


This is a clinical research study designed to evaluate whether the administration of a
vaccine to patients after transplant consisting of a minor histocompatibility antigen (mHag
peptide) mixed with G-CSF (a drug intended to stimulate the immune system) can stimulate
increased graft versus leukemia (GVL) responses without causing graft-versus-host disease
(GVHD).



We found this trial at
1
site
5801 South Ellis Avenue
Chicago, Illinois 60637
 773.702.1234
University of Chicago One of the world's premier academic and research institutions, the University of...
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mi
from
Chicago, IL
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