Application of Magnetic Resonance Fat-Free Imaging
| Status: | Completed |
|---|---|
| Conditions: | Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 2/4/2013 |
| Start Date: | July 2009 |
| End Date: | July 2013 |
| Contact: | Samuel Singer, MD |
| Phone: | 212-639-2940 |
Magnetic resonance imaging (MRI) is presently the best study for assessing the size and
extent of the patient's sarcoma. Many sarcomas contain fat that can interfere with the
accuracy of sarcoma detection. The investigators have developed a new MRI method that can
suppress all the fat signals in the patient's tumor and this may improve the investigators'
ability to see the patient's sarcoma. The purpose of this study is to determine if the
investigators' new fat-free imaging methods provides them with images that are better than,
equal to, or worse than those images obtained by standard MRI methods. This study may help
the investigators develop a more accurate MRI examination.
In addition, we will perform the same scans on 4 volunteers who have no history of sarcoma.
Scanning volunteers will allow us to optimize the imaging technique by 1.) Determine the
best combination of pulse-sequence and magnetization transfer technique to obtain the
greatest contrast and 2.) Determine the parameters of repetition time (TR), echo time (TE)
and magnetization transfer time and power in order to reduce overall image acquisition time
while optimizing image quality. Honing this technique on volunteers will allow us to
decrease scan time and potential discomfort for patients.
Inclusion Criteria:
- Participant is capable of providing verbal consent.
- 18 years of age or older.
- Participants will belong to one of the following two categories:
- Patient with a known or suspected soft tissue sarcoma of the extremity or trunk who
is/will be scheduled for an MRI scan as part of their routine care, -OR--
- Volunteer with no history of sarcoma.
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