Study of the Effect of Differing Platelet Transfusion Times in Neonates



Status:Archived
Conditions:Hematology
Therapuetic Areas:Hematology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:May 2009
End Date:October 2010

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The Effect of Variable Platelet Transfusion Durations on Platelet Count in Thrombocytopenic Newborns


To evaluate changes in platelet counts and hemodynamics between "rapid" and "long" platelet
infusion groups.


1. It is our hypothesis that the change in post-transfusion platelet counts of babies who
receive platelets over 30 minutes (short transfusion group) will be significantly
different from the change in babies who receive platelets over two hours (long
transfusion group) when platelets are checked immediately after transfusion and 6 hours
after the completion of transfusion.

2. We also expect there to be significant differences in the platelet counts drawn thirty
minutes after transfusion compared to the counts drawn 6 hours after the completion of
the transfusion in either group.

3. We aim to evaluate the hemodynamic changes in response to transfusion as assessed by
echocardiography.


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