A Long Term Extension Study Evaluating ACC-001 With QS-21 in Subjects With Mild to Moderate Alzheimer's Disease



Status:Terminated
Conditions:Alzheimer Disease
Therapuetic Areas:Neurology
Healthy:No
Age Range:50 - 85
Updated:4/21/2016
Start Date:July 2009
End Date:December 2013

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A Phase 2a, Multicenter, Randomized, Third-party Un-blinded, Long-term Extension Study To Determine Safety, Tolerability, And Immunogenicity Of Acc-001 With Qs-21 Adjuvant In Subjects With Mild To Moderate Alzheimer Disease

The purpose of this study is to assess the long term safety, tolerability, and
immunogenicity of ACC-001, an investigational vaccine, plus QS-21 in subjects with mild to
moderate Alzheimer's disease.


Inclusion Criteria:

Subjects randomized under previous 3134K1-2201 study (NCT00498602) and met all
inclusion/and none of the exclusion criteria.

Screening brain MRI scan is consistent with the diagnosis of AD.

Mini-Mental State Examination (MMSE) score greater than or equal to 10.

Other criteria apply.

Exclusion Criteria:

Significant Neurological Disease other than Alzheimer's disease.

Current clinically significant systemic illness.

Other exclusion criteria apply.
We found this trial at
22
sites
Boston, Massachusetts 02115
643
mi
from 43215
Boston, MA
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911 E. Hallandale Beach Blvd
Hallandale Beach, Florida 33009
954-455-5757
980
mi
from 43215
Hallandale Beach, FL
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Bennington, Vermont 05201
547
mi
from 43215
Bennington, VT
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Bennington, Vermont 05201
546
mi
from 43215
Bennington, VT
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Bennington, Vermont
547
mi
from 43215
Bennington, VT
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Boston, Massachusetts 02215
643
mi
from 43215
Boston, MA
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Eatontown, New Jersey 07724
473
mi
from 43215
Eatontown, NJ
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20 York St, N20 York St,
New Haven, Connecticut 06520
(203) 688-4242
Yale-New Haven Hospital Relying on the skill and expertise of more than 4,500 university and...
537
mi
from 43215
New Haven, CT
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333 Cedar St
New Haven, Connecticut 06504
(203) 432-4771
Yale University School of Medicine Founded in 1810, the Yale School of Medicine is a...
537
mi
from 43215
New Haven, CT
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New York, New York 10032
442
mi
from 43215
New York, NY
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New York, New York 10032
481
mi
from 43215
New York, NY
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Phoenix, Arizona 85006
1660
mi
from 43215
Phoenix, AZ
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345 Blackstone Blvd
Providence, Rhode Island 02906
(401) 455-6200
Butler Hospital Founded in 1844, Butler Hospital is the state's only non-profit, free-standing psychiatric hospital...
619
mi
from 43215
Providence, RI
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San Francisco, California 94143
2109
mi
from 43215
San Francisco, CA
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1 Barnes Jewish Hospital Plaza
St. Louis, Missouri 63110
(314) 747-3000
Barnes Jewish Hospital Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in...
397
mi
from 43215
St. Louis, MO
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St. Louis, Missouri 63108
397
mi
from 43215
St. Louis, MO
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397
mi
from 43215
St. Louis, MO
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Sun City, Arizona 85351
1668
mi
from 43215
Sun City, AZ
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Sun City, Arizona 85351
1669
mi
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Sun City, AZ
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Washington, District of Columbia 20007
325
mi
from 43215
Washington,
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3800 Reservoir Rd NW
Washington, District of Columbia 20007
(202) 687-7695
Georgetown University Medical Center Georgetown University Medical Center is committed to excellence in research, education...
328
mi
from 43215
Washington,
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931
mi
from 43215
West Palm Beach, FL
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