A Study for Image-Guided Radiation Therapy in Pediatric Brain Tumors and Side Effects



Status:Archived
Conditions:Brain Cancer, Neurology
Therapuetic Areas:Neurology, Oncology
Healthy:No
Age Range:Any
Updated:7/1/2011

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A Phase II Study of Image-Guided Radiation Therapy for Pediatric CNS Tumors and Quantification of Radiation-Related CNS Effects


The purpose of the study is to determine if Image-Guided Radiation Therapy has less side
effects than standard radiation therapy, without affecting the success of radiation
treatment and to examine the effect of radiation on learning, thinking, hearing, and the
production of hormones.


Radiation therapy is commonly used to treat low-grade gliomas, low-grade non-glial neoplasms
and high grade gliomas. The ability of the therapy to control disease varies depending on
the location of the tumor. Children who receive Image-Guided Radiation Therapy (IGRT) for
brain tumors are currently being followed for a period of ten years following treatment to
evaluate tumor response to treatment. This study will collect information before and during
long term follow-up (10 years) for patients who receive Image-Guided Radiation Therapy as
treatment for brain tumors. Information about long term control of the disease and the
effects of the treatment on patients' functional abilities will be made available by
studying the patient for a longer period of time.


We found this trial at
1
site
St. Louis, Missouri 63108
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St. Louis, MO
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