Topical Budesonide Treatment for Eosinophilic Esophagitis (EoE)



Status:Archived
Conditions:Gastrointestinal
Therapuetic Areas:Gastroenterology
Healthy:No
Age Range:Any
Updated:7/1/2011
Start Date:October 2009
End Date:June 2011

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Trial Summary
Trial Overview
Inclusion Criteria

Topical Budesonide Treatment for Eosinophilic Esophagitis (EoE): Esophageal Medication Distribution, Treatment Response, and Effect on the Adrenal Axis.


The purpose of this study is to conduct a clinical trial of two formulations of budesonide
(nebulized/swallowed versus viscous/swallowed) in patients with EoE to determine if
medication contact time and distribution in the esophagus relates to treatment response.
The investigators will also determine if there is systemic absorption of these topical
steroids. The investigators hypothesize that tissue and symptom response will correlate
with esophageal medication contact time and distribution, and that significant systemic
absorption will not be seen.



We found this trial at
1
site
University of North Carolina Hospital at Chapel Hill
101 Manning Dr
Chapel Hill, North Carolina 27599
(919) 966-4131
University of North Carolina Hospital at Chapel Hill The UNC Health Care System is a...
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mi
from
Chapel Hill, NC
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