The Renin-Aldosterone Axis in Postural Tachycardia Syndrome
| Status: | Completed |
|---|---|
| Conditions: | Cardiology |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 64 |
| Updated: | 8/19/2018 |
| Start Date: | April 2009 |
| End Date: | December 2012 |
The purpose of this study is to determine the role of the renin-angiotensin-aldosterone in
the pathophysiology of postural tachycardia syndrome, and to provide an insight about the
disease process in this disorder.
the pathophysiology of postural tachycardia syndrome, and to provide an insight about the
disease process in this disorder.
Inclusion Criteria:
- Diagnosis of postural tachycardia syndrome by the Vanderbilt Autonomic Dysfunction
Center criteria
- Age between 18-64 years
- Male or females are eligible
- Able and willing to provide informed consent
- Healthy control subjects with no major medical problem (including postural tachycardia
syndrome), free of medications during the study
Exclusion Criteria:
- Overt cause of postural tachycardia e.g., dehydration
- Inability to give or withdraw informed consent
- Pregnancy
- Hypertension (BP > 140/90)
- Significant co-morbid condition
- Other factors which in the investigator`s opinion would prevent the subject from
completing the protocol
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