Effect of Genetic Variants in the Xenobiotic Transporter, OCT1, on Response to Metformin in Healthy Subjects
| Status: | Archived |
|---|---|
| Conditions: | Healthy Studies |
| Therapuetic Areas: | Other |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 7/1/2011 |
Specific Objectives:
- To determine if individuals who carry a decreased or non-functional variant of OCT1
exhibit differences in the pharmacokinetics of metformin in comparison to individuals
who carry the common allele.
- To determine if individuals who carry the decreased or non-functional variants exhibit
differences in the response to metformin in comparison to individuals who carry the
common allele.
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San Francisco General Hospital San Francisco General Hospital and Trauma Center (SFGH) is an essential...
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