Translating Dietary Trials Into the Community

Hypertension (HTN) is a prevalent risk factor for cardiovascular, cerebrovascular, and renal
disease, and disproportionately affects African Americans (AA). Although HTN awareness and
treatment rates among AA are similar to, or exceed non-Hispanic whites, control of HTN among
AAs remains inadequate. Randomized clinical trials have demonstrated the effectiveness of
lifestyle measures in lowering BP, including the Dietary Approaches to Stop Hypertension
(DASH) diet, which lowers systolic BP 6-14 mmHg. DASH calls for increased consumption of
fruits, vegetables, and low fat dairy, and decreased saturated fat and sodium intake. There
is limited evidence that DASH has been widely adopted by the public and AA from lower income
communities may be less able to adopt DASH as currently disseminated due to barriers related
to income, education, attitudes about foods, health beliefs, and neighborhood availability of
healthier foods. We propose to utilize quantitative and qualitative research techniques
(including focus groups and surveys) to assess environmental, intra-personal, interpersonal
and cultural factors that could affect the translation of the DASH diet in a low-income AA
community, then utilize the knowledge gathered to adapt existing intervention strategies and
tools. These will provide the materials for a randomized three month pilot lifestyle
intervention implementing the DASH diet. The 40 participants will be aged 21+ and have
pre-HTN or HTN with blood pressure between 120-150/80-95 mmHg on 0,1 or 2 antihypertensive
agents, and will be AA residents of two zip codes in Winston-Salem (a lower-income area whose
population is significantly minority).

Inclusion Criteria:

- Being African American

- Age 21 years or older

- Residing in zip code 27105 or 27101

- Formal education less than 4-year college degree

- Blood pressure between 120/80 mmHg and 150/95 mmHg, inclusive (patients on BP lowering
drugs eligible if BP is in above range)

- Willing to provide informed consent

- Able to participate in English

Exclusion Criteria:

- Clinical history of congestive heart failure

- Clinical history of diabetes, or newly diagnosed diabetes at screening

- Clinical history of renal insufficiency (Stage 3 or higher chronic kidney disease)

- BMI less than or equal to 18.5 kg/m2 or greater than or equal to 45.0 kg/m2

- Pregnancy

- Non-English speaker