Erlotinib Is Being Studied With Or Without An Investigational Drug, PF-02341066, In Patients With Lung Cancer
| Status: | Completed |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | January 2010 |
| End Date: | January 2014 |
Phase 1/2, Open Label, Randomized Study Of The Safety, Efficacy, And Pharmacokinetics Of Erlotinib With Or Without Pf 02341066 In Patients With Advanced Non Small Cell Adenocarcinoma Of The Lung.
This is a Phase 1/2 study comparing the safety and anti-tumor activity of erlotinib alone
versus erlotinib in combination with PF-02341066 in patients with advanced non-small cell
lung cancer.
versus erlotinib in combination with PF-02341066 in patients with advanced non-small cell
lung cancer.
Inclusion Criteria:
- histologically proven diagnosis of Non-Small Cell Lung Cancer (NSCLC) that is locally
advanced or metastatic and of the adenocarcinoma subtype (including mixed
adenosquamous histology)
- evident disease progression by Response Evaluation Criterion in Solid Tumors (RECIST)
after at least one but no more than 2 chemotherapy regimens for advanced disease
- tumors must have measurable disease as per RECIST
Exclusion Criteria:
- known interstitial lung disease
- prior treatment with an agent that is known or proposed to be active by action on
EGFR tyrosine kinase or c-Met/HGF (Phase 2 Portion)
We found this trial at
15
sites
Click here to add this to my saved trials
University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
Click here to add this to my saved trials
Holy Cross Hospital While spirituality plays an essential role in the way that we minister...
Click here to add this to my saved trials
Seattle Cancer Care Alliance Seattle Cancer Care Alliance (SCCA) is a cancer treatment center that...
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials
University of Washington Medical Center University of Washington Medical Center is one of the nation's...
Click here to add this to my saved trials
Barnes Jewish Hospital Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in...
Click here to add this to my saved trials
Click here to add this to my saved trials
Click here to add this to my saved trials