Erlotinib Is Being Studied With Or Without An Investigational Drug, PF-02341066, In Patients With Lung Cancer
| Status: | Completed |
|---|---|
| Conditions: | Lung Cancer, Cancer |
| Therapuetic Areas: | Oncology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/21/2016 |
| Start Date: | January 2010 |
| End Date: | January 2014 |
Phase 1/2, Open Label, Randomized Study Of The Safety, Efficacy, And Pharmacokinetics Of Erlotinib With Or Without Pf 02341066 In Patients With Advanced Non Small Cell Adenocarcinoma Of The Lung.
This is a Phase 1/2 study comparing the safety and anti-tumor activity of erlotinib alone
versus erlotinib in combination with PF-02341066 in patients with advanced non-small cell
lung cancer.
versus erlotinib in combination with PF-02341066 in patients with advanced non-small cell
lung cancer.
Inclusion Criteria:
- histologically proven diagnosis of Non-Small Cell Lung Cancer (NSCLC) that is locally
advanced or metastatic and of the adenocarcinoma subtype (including mixed
adenosquamous histology)
- evident disease progression by Response Evaluation Criterion in Solid Tumors (RECIST)
after at least one but no more than 2 chemotherapy regimens for advanced disease
- tumors must have measurable disease as per RECIST
Exclusion Criteria:
- known interstitial lung disease
- prior treatment with an agent that is known or proposed to be active by action on
EGFR tyrosine kinase or c-Met/HGF (Phase 2 Portion)
We found this trial at
15
sites
Holy Cross Hospital While spirituality plays an essential role in the way that we minister...
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University of Alabama at Birmingham The University of Alabama at Birmingham (UAB) traces its roots...
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Seattle Cancer Care Alliance Seattle Cancer Care Alliance (SCCA) is a cancer treatment center that...
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University of Washington Medical Center University of Washington Medical Center is one of the nation's...
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Barnes Jewish Hospital Barnes-Jewish Hospital at Washington University Medical Center is the largest hospital in...
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