Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis

Status:	Completed
Conditions:	Hospital, Gastrointestinal
Therapuetic Areas:	Gastroenterology, Other
Healthy:	No
Age Range:	Any
Updated:	5/5/2014
Start Date:	December 2012
End Date:	December 2014
Contact:	Marc H Gorelick, MD
Email:	mgorelic@mcw.edu
Phone:	414-266-2625

Impact of Emergency Department Probiotic Treatment of Pediatric Gastroenteritis: Randomized Controlled Trial

The purpose of this study is to determine whether administration of a probiotic agent
(Lacidofil) is effective in reducing the severity of acute infectious gastroenteritis among
children evaluated in North American emergency departments.

Inclusion Criteria:

- age 3-48 months

- diarrhea (3 or more watery stools in a 24-hour period) for 2 days or less

- evaluated in a participating emergency department in US or Canada

- diagnosis of acute gastroenteritis by treating physicians

Exclusion Criteria:

- patient or household member with immunodeficiency or immunosuppressive therapy

- hematochezia in the preceding 48 hours

- patient or household member with indwelling vascular access line

- bilious vomiting or other signs of intestinal obstruction

- probiotic use in the preceding 2 weeks

- cow's milk protein allergy

- follow-up not possible

We found this trial at

sites

Morgan Stanley Children's Hospital of New York

New York, New York 10032

from

New York, NY