Omega-3 Fatty Acids for Prevention of Post-Operative Atrial Fibrillation
| Status: | Completed |
|---|---|
| Conditions: | Atrial Fibrillation |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | Any |
| Updated: | 2/4/2013 |
| Start Date: | August 2010 |
| End Date: | May 2012 |
| Contact: | Dariush Mozaffarian, MD DrPH |
| Email: | dmozaffa@hsph.harvard.edu |
(OPERA)Randomized Clinical Trial to Examine Whether Peri-operative Intake of n-3 Polyunsaturated Fatty Acids Will Reduce the Occurrence of Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery
This is a large multi-center study to examine whether peri-operative intake of n-3
polyunsaturated fatty acids (PUFA) will reduce the occurrence of post-operative atrial
fibrillation or flutter (AF) in patients undergoing cardiac surgery (CS).
Inclusion Criteria:
- Age 18 years or over
- Scheduled for CS on the following day or later, including coronary artery bypass,
valve surgery, any other open cardiac surgery (i.e., that includes opening of the
pericardium), or any combination.
- Sinus rhythm on current ECG (sinus bradycardia, sinus tachycardia, and ectopy are
acceptable).
Exclusion Criteria:
- Regular use (3 or more days/week) of fish oil within the past 4 weeks.
- Known allergy or intolerance to fish oil or corn oil.
- Currently pregnant.
- Unable to provide informed written consent.
- Current or planned cardiac transplant or LVAD
We found this trial at
1
site
Click here to add this to my saved trials
