Voyager I: Patient Discharge Using the AB5000 Portable Driver System

Inclusion Criteria:

- The subject is an AB5000 Circulatory Support System patient (in accordance
FDA-approved indications for use) who is suffering acute cardiac dysfunction and is
potentially recoverable;

- The subject is male or female, age 18 years or older;

- The subject is able to ambulate unassisted;

- The subject is on stable oral anticoagulation over 7 days (INR 2-4) with no active
bleeding;

- The subject is willing and able to read, understand and sign the study specific
informed consent form;

- The subject agrees to comply with study protocol requirements, including all
follow-up visits and completion of Qol and NIH stroke scale assessments.

Exclusion Criteria:

- The subject, pre-device implant, is qualified as a transplant candidate.

- There is an absence of a trained companion.

- There is an absence of a psycho-social support.

- The subject has an inadequate home environment, such as poor access which may hinder
movements.

- The subject has experienced hypotension in last 24 hours based on two consecutive
readings spaced by 8 hours with systolic blood pressures < 90 mmHg.

- The subject requires respiratory assistance.

- The subject has an active infection (positive blood culture and/or body T ≥ 38
degrees C, and/or WBC ≥ 12K/µL).

- The subject requires tube feeding.

- The subject has any other medical condition requiring hospitalization.