Effectiveness Study of Single Photon Emission Computed Tomography (SPECT) Versus Positron Emission Tomography (PET) Myocardial Perfusion Imaging
Status: | Completed |
---|---|
Conditions: | Peripheral Vascular Disease, Cardiology |
Therapuetic Areas: | Cardiology / Vascular Diseases |
Healthy: | No |
Age Range: | 30 - 90 |
Updated: | 11/8/2014 |
Start Date: | June 2009 |
End Date: | September 2014 |
Contact: | Timothy M Bateman, M.D. |
Email: | tbateman@cc-pc.com |
Phone: | 816-751-8542 |
Clinical Effectiveness of Pharmacologic Stress Radionuclide Myocardial Perfusion Imaging as a Guide to Management of Patients With Known CAD: Comparison of Single-Photon Emission Computed Tomography (SPECT) and Positron Emission Tomography (PET)
The purpose of this study is to compare pharmacologic stress myocardial perfusion PET with
pharmacologic stress myocardial perfusion SPECT in a near-simultaneous, head-to-head
comparison in the same patient. The investigators hypothesize that pharmacologic stress
myocardial perfusion PET will prove superior to pharmacologic stress myocardial perfusion
SPECT as a first-line diagnostic test for higher-risk patients with known coronary artery
disease (CAD) who present with symptoms consistent with possible worsening of their CAD.
pharmacologic stress myocardial perfusion SPECT in a near-simultaneous, head-to-head
comparison in the same patient. The investigators hypothesize that pharmacologic stress
myocardial perfusion PET will prove superior to pharmacologic stress myocardial perfusion
SPECT as a first-line diagnostic test for higher-risk patients with known coronary artery
disease (CAD) who present with symptoms consistent with possible worsening of their CAD.
Inclusion Criteria:
- History of coronary artery disease
- New or worsening symptoms
- Out-patients and in-hospital patients
Exclusion Criteria:
- Creatinine above 2.5 mg%
- PCI within prior 6 months
- Pregnant females
- Cardiomyopathy (LVEF below 40%)
- Significant valvular heart disease
- Body mass index greater than 38
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