Effects of Delta-9-THC and Iomazenil in Healthy Humans
| Status: | Active, not recruiting |
|---|---|
| Conditions: | Schizophrenia, Psychiatric |
| Therapuetic Areas: | Psychiatry / Psychology |
| Healthy: | No |
| Age Range: | 18 - 55 |
| Updated: | 1/11/2019 |
| Start Date: | February 2009 |
| End Date: | June 2019 |
Gamma-Amino Butyric Acid (GABA) Deficits and Vulnerability to Cannabinoid-Induced Psychosis
The study aims to examine the combined effects of delta-9-tetrahydrocannabinol (∆-9-THC or
THC) and iomazenil on thinking, perception, mood, memory, attention, and electrical activity
of the brain (EEG). THC is the active ingredient of marijuana, cannabis, "ganja", or "pot".
Iomazenil is a drug that works opposite to drugs like valium. The purpose of this study is to
determine whether the administration of iomazenil will alter the effects of THC.
THC) and iomazenil on thinking, perception, mood, memory, attention, and electrical activity
of the brain (EEG). THC is the active ingredient of marijuana, cannabis, "ganja", or "pot".
Iomazenil is a drug that works opposite to drugs like valium. The purpose of this study is to
determine whether the administration of iomazenil will alter the effects of THC.
Inclusion Criteria:
- Exposed to cannabis at least once in their lifetime
Exclusion Criteria:
- Cannabis naïve
- History of hearing deficit
We found this trial at
1
site
950 Campbell Ave
West Haven, Connecticut 06516
West Haven, Connecticut 06516
(203) 932-5711
Principal Investigator: Deepak C D'Souza, M.D.
VA Connecticut Healthcare System VA Connecticut encompasses an inpatient facility and Ambulatory Care Center in...
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