A Trial Comparing Prograf and Neoral Use in Kidney Transplant Recipients of Hispanic Ethnicity

This study aims to include Hispanics who have undergone a renal transplant to determine the
specific outcome after renal transplantation, assuming that ethnic groups require different
immunosuppressant regimens. Trough levels in transplant recipients determine the dosing
requirements for Tacrolimus and Cyclosproine. It has been recently found, however, that
testing cyclosporine levels in the blood 2 hours after taking cyclosporine is more effective
in dosing cyclosprine for renal transplant patients than trough levels. The specific study
aims include comparing the cyclosporine monitoring in patients with trough and C2 levels,
and adjusting immunosuppression based on C2 levels.

Inclusion Criteria:

- Cadaveric or Living Donors

- 18 years old or greater

- Primary renal transplants

- Hispanic ethnicity

Exclusion Criteria:

- Prior renal transplant

- Multi-organ transplant

- Recipient with history of Diabetes Mellitus

- PRA > 20%

- Cold Ischemia Time > 24 hours