Gestational Diabetes Mellitus and Cardiovascular Disease: The Role of Vascular Dysfunction



Status:Completed
Conditions:Peripheral Vascular Disease, Cardiology, Women's Studies, Diabetes
Therapuetic Areas:Cardiology / Vascular Diseases, Endocrinology, Reproductive
Healthy:No
Age Range:18 - 40
Updated:4/2/2016
Start Date:August 2009
End Date:January 2014
Contact:Research Assistant
Email:RBLResearchGroup@partners.org
Phone:617-724-3504

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The purpose of this research study is to look at whether there are differences in blood
vessel function, risk for developing diabetes (high blood sugar), lipid (blood fat) levels,
and levels of other blood markers between black women and white women who have or do not
have gestational diabetes mellitus.


Inclusion Criteria:

- Healthy women of self-identified African descent (black) and European (white)
ancestry,

- 18-40 years of age,

- Body mass index < 35 kg/m2

- History of regular menstrual cycles,

- Are currently pregnant and in third trimester of pregnancy (after 24 weeks
gestational age)

- Have no pregnancy-associated complications to-date

- Are in good health free of hypertension, as well as thyroid, cardiac, or renal
disease.

Exclusion Criteria:

- History of smoking

- Are taking potentially vasoactive medications
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