Nipple Sparing Mastectomy - Cosmetic Outcomes

The outcomes will be observed in patients with both known cancer diagnosis and in those with
indications for prophylactic mastectomy. The cosmetic appearance and complications will be
followed through several post operative visits throughout the duration of the study. This
study is conducted in conjunction with the plastic and reconstructive surgeons who will be
performing the breast reconstruction procedures. Patient satisfaction will be measured via
survey format. In addition, local recurrence rates will be compared to patients undergoing
traditional mastectomy.

Inclusion Criteria:

- Patients requiring mastectomy for cancer and/or prophylaxis

- Age greater than or equal to 18 at time of surgery

- BMI less than or equal to 35

- If mastectomy is indicated for removal of breast cancer, tumor is clinically T1 or T2

Exclusion Criteria:

- Currently smoking

- Prior radiation to the affected breast

- Systemic lupus erythematosus

- Central tumor location and/or tumor within 2 cm of NAC

- Paget's disease of the nipple

- Clinical evidence of tumor involvement in the nipple

- Clinical evidence of axillary nodal tumor involvement

- Lymphovascular invasion of the tumor on core biopsy