Detection and Quant of Differences in Hodgkin Lymphoma and Diffuse Large B-cell Lymphoma Using Positron Emission Tomography/Computed Tomography (PET/CT)



Status:Completed
Conditions:Lymphoma
Therapuetic Areas:Oncology
Healthy:No
Age Range:18 - Any
Updated:11/8/2014
Start Date:May 2009
End Date:May 2013
Contact:Stephen Schuster, MD
Email:PennCancerTrials@emergingmed.com
Phone:855-216-0098

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A Pilot Study to Assess the Feasibility of Detection and Quantification of Differences in Hodgkin Lymphoma and Diffuse Large B-cell Lymphoma Using FDG-PET/CT Imaging

RATIONALE: Imaging procedures, such as positron emission tomography or computed tomography,
may help in detecting differences between Hodgkin lymphoma or diffuse large B-cell lymphoma
cancer cells. PURPOSE: This clinical trial is studying positron emission tomogaphy and
computed tomography in determining differences in Hodgkin lymphoma and diffuse large B-cell
lymphoma.

OBJECTIVES:

I. Assess the feasibility of detection and quantification of differences in the temporal and
spatial distribution of FDG uptake between lesions of HL and DLBCL.

OUTLINE:

Patients undergo fludeoxyglucose F18 (FDG) positron emission tomography/computed tomography
scans 60 and 180 minutes after FDG administration.

After completion of study, patients are followed for 24 hours.

Inclusion Criteria:

- Subjects with a pathologically-proven diagnosis of classic HL or DLBCL with
measurable disease by any imaging technique or physical examination.

Exclusion Criteria:

- Pregnant or nursing,

- Uncontrolled diabetes mellitus,

- Active infection,

- Inability to give informed consent or to comply with all study procedures,

- Subjects may be excluded at the discretion of the principal investigator or study
team members.
We found this trial at
1
site
3400 Civic Center Blvd
Philadelphia, Pennsylvania 19104
(215) 662-6065
Abramson Cancer Center of the University of Pennsylvania The Abramson Cancer Center of the University...
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from
Philadelphia, PA
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