Tetracaine Combined Spinal Epidural (CSE) Versus Bupivacaine CSE
| Status: | Terminated |
|---|---|
| Conditions: | Women's Studies |
| Therapuetic Areas: | Reproductive |
| Healthy: | No |
| Age Range: | 12 - Any |
| Updated: | 11/10/2017 |
| Start Date: | August 2009 |
| End Date: | December 12, 2011 |
Comparison of Spinal Tetracaine With Fentanyl and Epinephrine Versus Bupivacaine With Fentanyl and Epinephrine for Combined Spinal Epidural Labor Analgesia
The investigators hypothesis is that spinal tetracaine with fentanyl and epinephrine used for
CSE labor analgesia volume will last a significantly longer period of time that that of
spinal bupivacaine with fentanyl. After informed consent is obtained for the study, subjects
meeting criteria when analgesia is requested will be randomized to receive a combined
spinal-epidural containing either tetracaine 2 mg with fentanyl and epinephrine or
bupivacaine 2 mg with fentanyl and epinephrine.
CSE labor analgesia volume will last a significantly longer period of time that that of
spinal bupivacaine with fentanyl. After informed consent is obtained for the study, subjects
meeting criteria when analgesia is requested will be randomized to receive a combined
spinal-epidural containing either tetracaine 2 mg with fentanyl and epinephrine or
bupivacaine 2 mg with fentanyl and epinephrine.
Inclusion Criteria:
- early labor (>=2cm but =<6cm cervical dilation)
- at least 12 years of age
- have an assigned ASA physical status 1 or 2
- singleton pregnancy
Exclusion Criteria:
- contraindications to neuraxial anesthesia
- with allergies to drugs used in the study
- have an assigned ASA status 3 or 4
- advanced labor (> 6cm cervical dilation)
- less than 12 years of age
- Patients with the potential for distorted epidural anatomy, such as Harrington rods or
prior back surgery, will also be excluded.
We found this trial at
1
site
3333 Silas Creek Parkway
Winston-Salem, North Carolina 27103
Winston-Salem, North Carolina 27103
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