Vitamin D for Chronic Sinusitis
| Status: | Recruiting |
|---|---|
| Conditions: | Sinusitis |
| Therapuetic Areas: | Otolaryngology |
| Healthy: | No |
| Age Range: | 18 - Any |
| Updated: | 4/2/2016 |
| Start Date: | November 2009 |
| End Date: | October 2016 |
| Contact: | Marcy deTineo, BSN |
| Email: | mdetineo@surgery.bsd.uchicago.edu |
| Phone: | 773-702-5889 |
A Randomized, Clinical Trial of a Novel Immunotherapy for Chronic Sinusitis: Vitamin D
The purpose of this study is to examine if vitamin D improves the symptoms of chronic
sinusitis.
sinusitis.
Inclusion Criteria:
- African American (4 grandparents with AA ancestry)
- Age>18 years
- Diagnosis of chronic sinusitis
Exclusion Criteria:
- Women of childbearing potential not utilizing contraception
- Subjects with contraindications to vitamin D therapy
- History of nephrolithiasis, hypercalcemia, sarcoidosis, recent (3 month)
hospitalization
- Use of immunosuppressants/medications that interfere with vitamin D metabolism (e.g.,
phenytoin and carbamazepine)
- Malignancy
- Kidney, gastrointestinal, or liver disorders
- Immunodeficiency
- Morbid obesity (BMI>35 kg/m2)
- Changes to medications for 6 months prior to study entry
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