Genetic Mechanisms in Human Hypertension Renin-angiotensin-aldosterone System (RAAS) Inhibition Study
| Status: | Terminated |
|---|---|
| Conditions: | High Blood Pressure (Hypertension) |
| Therapuetic Areas: | Cardiology / Vascular Diseases |
| Healthy: | No |
| Age Range: | 18 - 65 |
| Updated: | 3/23/2019 |
| Start Date: | January 2007 |
| End Date: | March 19, 2019 |
Genetic Mechanisms in Human Hypertension RAAS Inhibition Study
The purpose of this study is to develop an approach to provide personalized medicine to
individuals who have hypertension (high blood pressure). The investigators plan to use
people's genetic characteristics (traits) to determine what medication they should use to
lower their blood pressure most effectively. The investigators will give individuals one of
two medications to treat hypertension (lisinopril or atenolol). The investigators believe
that depending on the individuals genetic background one medication will work better in
lowering their blood pressure.
individuals who have hypertension (high blood pressure). The investigators plan to use
people's genetic characteristics (traits) to determine what medication they should use to
lower their blood pressure most effectively. The investigators will give individuals one of
two medications to treat hypertension (lisinopril or atenolol). The investigators believe
that depending on the individuals genetic background one medication will work better in
lowering their blood pressure.
Inclusion Criteria:
- Male and female hypertensive participants who were previously studied in SCOR program.
Exclusion Criteria:
- Diabetes
- Taking other medications beside thyroid or estrogen supplements.
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